ID   A0A3Q7ULG1_VULVU        Unreviewed;      1185 AA.
AC   A0A3Q7ULG1;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Sorbin and SH3 domain-containing protein 2 isoform X13 {ECO:0000313|RefSeq:XP_025874012.1};
GN   Name=SORBS2 {ECO:0000313|RefSeq:XP_025874012.1};
OS   Vulpes vulpes (Red fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX   NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025874012.1};
RN   [1]
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (JAN-2019) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_025874012.1}
RP   IDENTIFICATION.
RC   STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025874012.1};
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_025874012.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_025874012.1; XM_026018227.1.
DR   AlphaFoldDB; A0A3Q7ULG1; -.
DR   Proteomes; UP000286640; Unplaced.
DR   CDD; cd11923; SH3_Sorbs2_2; 1.
DR   CDD; cd11917; SH3_Sorbs2_3; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 3.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   InterPro; IPR003127; SoHo_dom.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PANTHER; PTHR14167:SF56; DREBRIN-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR   Pfam; PF00018; SH3_1; 2.
DR   Pfam; PF14604; SH3_9; 1.
DR   Pfam; PF02208; Sorb; 1.
DR   PRINTS; PR00499; P67PHOX.
DR   PRINTS; PR00452; SH3DOMAIN.
DR   SMART; SM00326; SH3; 3.
DR   SMART; SM00459; Sorb; 1.
DR   SUPFAM; SSF50044; SH3-domain; 3.
DR   PROSITE; PS50002; SH3; 3.
DR   PROSITE; PS50831; SOHO; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          166..230
FT                   /note="SoHo"
FT                   /evidence="ECO:0000259|PROSITE:PS50831"
FT   DOMAIN          947..1006
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          1022..1083
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          1126..1185
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   REGION          25..96
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          216..394
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          895..949
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        25..62
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        77..96
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        216..246
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        252..267
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        268..298
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        311..335
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        366..390
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        904..918
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        935..949
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1185 AA;  133311 MW;  09398BE23D9C1F58 CRC64;
     MNTDSGGCAR KRAAMSVTLT SVKRVQSSPN LLAAGRDSQS PDSAWRSYND RNQETLNGDA
     TYSSLAAKGF RSVRPNLQEK KSPTQSQITV NGNSGGAVSP MSYYQRPFSP SAYSLPGSLN
     SSIIMQHGRS LDSTEAYPQH AQSLDGTMGS SIPLYRSSEE EKRVTVIKAP HYPGIGPVDE
     SGIPTAIRTT VDRPKDWYKT MFKQIHMVHK PGLYNSPYSA QSHPAAKTQT YRPLSKSHSD
     NGTDVFKDAS SPVPPPHVPP PVPPLRPRDR SSTEKHDWDP PDRKVDTRKF RSEPRSIFEY
     EPGKSSILQH ERPASLYQSS LDRSLERPTS SASMASDFRK RRKSEPAVGP PRGVDPSASR
     TSPGGADLPG PSTTLTKSYI ISSSPSSPSR AKGGDDICPS LYGYSGLNGN PSNELDYCNT
     YRQHLDVPRD SQRAITFKNG WQMARQNAEI WSSTEETVSP KIKSRSCDDL LNDDCDSFPD
     PKTKSESMGS LLCEEDSKES CPITWASSYI QEGRSNGRSR LRHRSAHDAP GFLKMYKKMH
     RINRKDLMNS EVICSVKSRI MQYEKEQQHK GLLHGWSQSS TEEVPRDMVP TRISEFEKLI
     QKSKSMPNLG DEMLSPITLE PPQNGLCPKR RFSIESLLEE ESQSRHPSHV QRSYKPKTVV
     PIHIEVTSDE QPRTHMEFSD SDQDGVVSDH SDYIHVEGSS FCSESDFDHF SFTSSESFYG
     SSHHHHHHHH HHHRHLISSC KGRCPASYTR FTTMLKHERA KHENSEEPRR QEMDPGLSKL
     AFLVSPVPFR RKKNSTPKKQ TEKAKCKASV FEALDSALKD ICDQIKAEKR RGSLPDNSIL
     HRLISELLPD IPERNSSLKA LKRSPMHQPF HPLPPDGAIH CPLYQNDCGR MPHSASFPDV
     DTASNYHHQD HESMQSLQDH ESPRSYASTM SDLGRSVPRD RRGTPEKEKL PAKAVYDFKA
     QTSKELSFKK GDTVYILRKI DQNWYEGEHH GRVGIFPISY VEKLTPPEKA QPARPPPPAQ
     PGEIGEAMAK YNFSADTNVE LSLRKGDRVI LLKRVDQNWY EGKIPGTSRQ GIFPVSYVEV
     IKKNTTKGAE NYPDPPIPHS YSSDRIHSLS SNKPQRPVFT HENIQGGGEP FQALYNYTPR
     NEDELELRES DVIDVMEKCD DGWFVGTSRR TKFFGTFPGN YVKRL
//