ID   A0A3Q7UPX3_VULVU        Unreviewed;       490 AA.
AC   A0A3Q7UPX3;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Arf-GAP domain and FG repeat-containing protein 2 isoform X1 {ECO:0000313|RefSeq:XP_025875292.1};
GN   Name=AGFG2 {ECO:0000313|RefSeq:XP_025875292.1};
OS   Vulpes vulpes (Red fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX   NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025875292.1};
RN   [1]
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (JAN-2019) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_025875292.1}
RP   IDENTIFICATION.
RC   STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025875292.1};
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_025875292.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_025875292.1; XM_026019507.1.
DR   AlphaFoldDB; A0A3Q7UPX3; -.
DR   KEGG; vvp:112935686; -.
DR   OrthoDB; 2891604at2759; -.
DR   Proteomes; UP000286640; Unplaced.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd17903; ArfGap_AGFG2; 1.
DR   Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR   InterPro; IPR037278; ARFGAP/RecO.
DR   InterPro; IPR001164; ArfGAP_dom.
DR   InterPro; IPR038508; ArfGAP_dom_sf.
DR   PANTHER; PTHR46134:SF4; ARF-GAP DOMAIN AND FG REPEAT-CONTAINING PROTEIN 2; 1.
DR   PANTHER; PTHR46134; DRONGO, ISOFORM F; 1.
DR   Pfam; PF01412; ArfGap; 1.
DR   PRINTS; PR00405; REVINTRACTNG.
DR   SMART; SM00105; ArfGap; 1.
DR   SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR   PROSITE; PS50115; ARFGAP; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00288}.
FT   DOMAIN          27..153
FT                   /note="Arf-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50115"
FT   REGION          150..219
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          455..490
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        186..218
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   490 AA;  50240 MW;  FF2908C1B51C6692 CRC64;
     MVMAAKKGPG PGGGVSGGKA EAEAASEVWC RRVRELGGCS QAGNRHCFEC AQRGVTYVDI
     TVGSFVCTTC SGLLRGLNPP HRVKSISMTT FTEPEVVFLQ SRGNEVCRKI WLGLFDARTS
     LIPDSRDPQK VKEFLQEKYE KKRWYVPPDQ VKGPAYTKGS ASTPIQGSIP EGKPLRTLLG
     DPVPSLSAAA STSSQSICQS QPRTSQPRSS QPPPHSSIKK ASTDLLADIG GDPFAAPQVA
     PAFAAFPAFG GQTPSHGGFA NFDAFGSSPG SSAFGSIPPA GQGPFQAQPT ATASRMLTGS
     YSFGSSQVTP FGASPLAPSQ PNSLPDMGSL LGPGASAGGI PSSVFGVAGQ VPALQSAPAG
     GGGGSTGLAF GAFTNPFTVP PTHAPLPSTN PFQPNGLGTG SSFGMSSIGP GFPQTVPPTR
     AFINTFPPPV FPPQTSMTQQ QNGSSFSDLG SAKLGQRQLS QPAGTSTNPF MTGSSSSPFA
     ARPSTTNPFL
//