ID A0A3Q7V6X1_VULVU Unreviewed; 943 AA.
AC A0A3Q7V6X1;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=General transcription factor II-I repeat domain-containing protein 1 isoform X1 {ECO:0000313|RefSeq:XP_025875370.1, ECO:0000313|RefSeq:XP_025875371.1};
GN Name=GTF2IRD1 {ECO:0000313|RefSeq:XP_025875370.1,
GN ECO:0000313|RefSeq:XP_025875371.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025875370.1};
RN [1]
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025875370.1, ECO:0000313|RefSeq:XP_025875371.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025875370.1,
RC ECO:0000313|RefSeq:XP_025875371.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025875370.1,
RC ECO:0000313|RefSeq:XP_025875371.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_025875370.1; XM_026019585.1.
DR RefSeq; XP_025875371.1; XM_026019586.1.
DR STRING; 9627.ENSVVUP00000034447; -.
DR Ensembl; ENSVVUT00000045376; ENSVVUP00000034416; ENSVVUG00000024859.
DR Ensembl; ENSVVUT00000045382; ENSVVUP00000034422; ENSVVUG00000024859.
DR KEGG; vvp:112935717; -.
DR OMA; VFDVLYX; -.
DR OrthoDB; 5308582at2759; -.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006366; P:transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 3.90.1460.10; GTF2I-like; 5.
DR InterPro; IPR004212; GTF2I.
DR InterPro; IPR036647; GTF2I-like_rpt_sf.
DR InterPro; IPR016659; TF_II-I.
DR PANTHER; PTHR46304; GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR46304:SF1; GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF02946; GTF2I; 5.
DR PIRSF; PIRSF016441; TF_II-I; 1.
DR SUPFAM; SSF117773; GTF2I-like repeat; 5.
DR PROSITE; PS51139; GTF2I; 5.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT REGION 230..250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 279..316
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 438..491
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 537..558
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 877..911
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 448..482
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 541..558
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 893..911
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 943 AA; 104670 MW; CF212076C9F938C8 CRC64;
MALLGKRCDI PANGCGPDRW NSAFTRKDEI ITSLVSALDS MCSALSKLNA EVACVAVHDE
SAFVVGTEKG RMFLNARKEL QSDFLRFCRG APWKEPEAEH PKKVLRGEGG GRNIPRSSLE
HGSDVYLLRK MVEEVFDVLY SEALGRASVV PLPYERLLRE PGLLAVQGLP EGLAFRRPAD
YDPKALMAIL EHSHRIRFKL KRPLEDGGRD SKALVELNGV SLIAKGSRDC GLHGQAPKGP
PQDLPPTATS SSVASFLYST ALPNHTTREL KQEASACPLA PSDLGLGRPG PEPKASGTQD
FADCCGQKPP GPGGPLIQNV HASKRILFSI VHDKSEKWDA FIKETEDINT LRECVQILFN
SRYAEALGLD HMVPVPYRKI ACDPEAVEIV GIPDKIPFKR PCTYGVPKLK RILEERHSIH
FIIKRMFDER IFTGNKFTKD PTKLEPASPP EDTSTELSRA TVLDLPGTTR SDKNSISEDC
GPGTSGELSG LRPIKIEPED LDIIQVTVPD PSPTSEEMTD SMPGHLPSED SGYGMEMLTE
KGPSEDPRPE ERPMEDSHGD VIRPLRKQVE LLFNTRYAKA IGISEPVKVP YSKFLMYPEE
LFVVGLPEGI SLRRPNCFGI AKLRKILEAS NSIQFVIKRP ELLTEGVKEP ITDSQERDSG
DPLVDESLKR QGFQENYDTR LSRIDIANTL REQVQDLFNK KYGEALGIKY PVQVPYKRIK
SNPGSVIIEG LPPGIPFRKP CTFGSQNLER ILAVADKIKF TVTRPFQGLI PKPDEDDANR
LGEKVILREQ VKELFNEKYG EALGLNRPVL VPYKLIRDSP DAVEVTGLPD DIPFRNPNTY
DIHRLEKILK AREHVRMVII NQLQPFAEIC NDAKVPAKDS SIPKRKRKRV SEGNSFSSSS
SSSSSSSNPE SVASTNQISL VQWPMYMVDY AGLNVQLPGP LNY
//
