ID A0A3Q7XHU2_CICAR Unreviewed; 409 AA.
AC A0A3Q7XHU2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=MLO-like protein {ECO:0000256|RuleBase:RU280816};
GN Name=LOC101508058 {ECO:0000313|RefSeq:XP_027193249.1};
GN Synonyms=MLO {ECO:0000256|RuleBase:RU280816};
OS Cicer arietinum (Chickpea) (Garbanzo).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Cicereae; Cicer.
OX NCBI_TaxID=3827 {ECO:0000313|Proteomes:UP000087171, ECO:0000313|RefSeq:XP_027193249.1};
RN [1] {ECO:0000313|RefSeq:XP_027193249.1}
RP IDENTIFICATION.
RC TISSUE=Etiolated seedlings {ECO:0000313|RefSeq:XP_027193249.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: May be involved in modulation of pathogen defense and leaf
CC cell death. {ECO:0000256|RuleBase:RU280816}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU280816}; Multi-
CC pass membrane protein {ECO:0000256|RuleBase:RU280816}.
CC -!- DOMAIN: The C-terminus contains a calmodulin-binding domain, which
CC binds calmodulin in a calcium-dependent fashion.
CC {ECO:0000256|RuleBase:RU280816}.
CC -!- SIMILARITY: Belongs to the MLO family. {ECO:0000256|ARBA:ARBA00006574,
CC ECO:0000256|RuleBase:RU280816}.
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DR RefSeq; XP_027193249.1; XM_027337448.1.
DR AlphaFoldDB; A0A3Q7XHU2; -.
DR Proteomes; UP000087171; Chromosome Ca1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0009607; P:response to biotic stimulus; IEA:UniProtKB-KW.
DR InterPro; IPR004326; Mlo.
DR PANTHER; PTHR31942; MLO-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR31942:SF9; MLO-LIKE PROTEIN 4; 1.
DR Pfam; PF03094; Mlo; 1.
PE 3: Inferred from homology;
KW Calmodulin-binding {ECO:0000256|RuleBase:RU280816};
KW Membrane {ECO:0000256|RuleBase:RU280816, ECO:0000256|SAM:Phobius};
KW Pathogenesis-related protein {ECO:0000256|ARBA:ARBA00023265,
KW ECO:0000256|RuleBase:RU280816};
KW Plant defense {ECO:0000256|RuleBase:RU280816};
KW Reference proteome {ECO:0000313|Proteomes:UP000087171};
KW Transmembrane {ECO:0000256|RuleBase:RU280816, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|RuleBase:RU280816,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 153..173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 409 AA; 47536 MW; E4D44AB978BDD7CA CRC64;
MEDVMHRGRS LAETPTYSVA SVVTVMVFVC FLVQRSIYRF GKWLKKTRRK ALFASLEKIK
EELMLLGLIS LLLAQSARWI SEICVNSSLF SSRFYTCAEQ HLGTIENIMI ENSSSLPDET
NIPKGLSSVA LHQCGEGHEP FVSYEGLEQL HRFLFVLGIT HVLYSCLAVA LAMSKIYSWC
RWENQAAMAT DANLQGKKNK VMRRQITFVF HRTSHPWSRS PILIWMLCFL RQFRSSIQKS
DYLALRLGFI TEHKLPLSYN FHKYMVRSME DEFHAILGIS WPLWIYTIVC IFVNIHGLNI
YFWISFIPAI LVMIIGTKLQ HVVSTLALEI REQQGPSART QVKPRDGLFW FKKPDILLWL
IQFVIFQNAF EMASFIWTLW GFKEKSCFMR HHYMIIIRLT SGFTDGIAM
//
