ID A0A3Q8VA78_9ACTN Unreviewed; 247 AA.
AC A0A3Q8VA78;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Short-chain dehydrogenase {ECO:0000313|EMBL:AZM59293.1};
GN ORFNames=DLM49_06715 {ECO:0000313|EMBL:AZM59293.1};
OS Streptomyces sp. WAC 01438.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2203204 {ECO:0000313|EMBL:AZM59293.1, ECO:0000313|Proteomes:UP000271045};
RN [1] {ECO:0000313|EMBL:AZM59293.1, ECO:0000313|Proteomes:UP000271045}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WAC 01438 {ECO:0000313|EMBL:AZM59293.1,
RC ECO:0000313|Proteomes:UP000271045};
RA Waglechner N., Wright G.D.;
RT "Evolution of GPA BGCs.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000256|ARBA:ARBA00006484}.
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DR EMBL; CP029601; AZM59293.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3Q8VA78; -.
DR OrthoDB; 9803333at2; -.
DR Proteomes; UP000271045; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd05233; SDR_c; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR InterPro; IPR002347; SDR_fam.
DR PANTHER; PTHR43669; 5-KETO-D-GLUCONATE 5-REDUCTASE; 1.
DR PANTHER; PTHR43669:SF3; OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_1G01330); 1.
DR Pfam; PF13561; adh_short_C2; 1.
DR PRINTS; PR00081; GDHRDH.
DR SMART; SM00822; PKS_KR; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00061; ADH_SHORT; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000271045}.
SQ SEQUENCE 247 AA; 25368 MW; F13F265D8204DA12 CRC64;
MGAYDGKTAV ITGGGSGLGL ATAKLLVDGG ARVVVNGRSK DTLDAALEEL GGNALAVQGD
VTSLSDLDEL AARVKDEFGT LDALFVNHGV TIPNPLESTT EELWDESMAI NLKGAFFTVQ
KLVPLMGPGA GVVLTTSAAN VMGLPECSAY SAGKAGLRSM ARTLSGDLLP RGIRVNAISP
GPIDTGILEK TMTAEAAEAF KAERVAQNPM RRFGRPEEIA KAAAFLAFDA TYTAGVELAV
DGGATQL
//
