ID A0A3Q9G2V7_STRLT Unreviewed; 680 AA.
AC A0A3Q9G2V7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
GN ORFNames=EKH77_26215 {ECO:0000313|EMBL:AZQ74247.1};
OS Streptomyces luteoverticillatus (Streptoverticillium luteoverticillatus).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=66425 {ECO:0000313|EMBL:AZQ74247.1, ECO:0000313|Proteomes:UP000267900};
RN [1] {ECO:0000313|EMBL:AZQ74247.1, ECO:0000313|Proteomes:UP000267900}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 15060 {ECO:0000313|EMBL:AZQ74247.1,
RC ECO:0000313|Proteomes:UP000267900};
RA Feng Z., Chen G., Zhang J., Zhu H., Yu X., Zhang W., Zhang X.;
RT "The whole draft genome of Streptomyce luteoverticillatus CGMCC 15060.";
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 33 family.
CC {ECO:0000256|ARBA:ARBA00009348}.
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DR EMBL; CP034587; AZQ74247.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3Q9G2V7; -.
DR OrthoDB; 7294637at2; -.
DR Proteomes; UP000267900; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR CDD; cd00110; LamG; 1.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.120.10.10; -; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006558; LamG-like.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR026856; Sialidase_fam.
DR InterPro; IPR036278; Sialidase_sf.
DR PANTHER; PTHR10628; SIALIDASE; 1.
DR PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR Pfam; PF13088; BNR_2; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR SMART; SM00282; LamG; 1.
DR SMART; SM00560; LamGL; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF50939; Sialidases; 1.
DR PROSITE; PS50025; LAM_G_DOMAIN; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000267900};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 40..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 470..652
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 293..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 680 AA; 72556 MW; 3FC58458A47FDC13 CRC64;
MAAHPSTSGS ADGESAGRPD GGSPGRPDGR RPRTLFRFRF RAAAVFVLSG ALLALALRPG
AAGATEEPVG PGRAGFDERV LFRADQDPGY ACYRIPAIVT TTHGTLLAFA EGRKDNCGDA
TDIDLVLKRS TDGGRSWGAL QIVDPGRGDT HGNPAPVVDR RTGRIVLATT YNEGREDAGN
CDVPCDRTPH LQYSDDDGVS WSWPRDITEE IRPPGWNSWY ATGPGHGVQL GHGPHEGRLV
IGLNAESHDG TRTSANHAAL ALSDDGGAHW RLGAVDTYPV AADRTYRQKP SELTLAERSD
GAVYAGGREQ DGTELGNRDD AVSGDGGESF DAPFRPLPDL YSPMVQGAVL PLPSGRWLFS
APADPDRRRT MTVRSSYDEG HTWESAERGR RVTADWSGYS DMAVIGQDTT GLLYEAGKAD
ARQEIRFARF TEEWLGPRRG PDPTTPDRAP GGTGAYVLGG ARPVGGRFGG GLGFDGTDSA
VRLPFRTALP LGTRDFTAAL WFRYRAAAVK GEQPLLWMGG VGGAPQVALR GEPGTGRVTG
QVTALAPGPG PSRTATVRSA DGYGDGRWHH VALRRSGGRL TLTVDGASAS VPDVPGSVSR
NSTFGVHLGQ RPDARAFLTG DLEEVRVYGR ALTDAELAAV RTHNTPVTRR DAVLWLPLDR
IDEPRKGRGE LRDQPPPARR
//
