ID A0A3Q9HQK8_9FIRM Unreviewed; 815 AA.
AC A0A3Q9HQK8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=DNA internalization-related competence protein ComEC/Rec2 {ECO:0000313|EMBL:AZR73201.1};
GN ORFNames=BBF96_07265 {ECO:0000313|EMBL:AZR73201.1};
OS Anoxybacter fermentans.
OC Bacteria; Bacillota; Clostridia; Halanaerobiales; Anoxybacter.
OX NCBI_TaxID=1323375 {ECO:0000313|EMBL:AZR73201.1, ECO:0000313|Proteomes:UP000267250};
RN [1] {ECO:0000313|EMBL:AZR73201.1, ECO:0000313|Proteomes:UP000267250}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DY22613 {ECO:0000313|EMBL:AZR73201.1,
RC ECO:0000313|Proteomes:UP000267250};
RA Zeng X., Shao Z.;
RT "Genome and transcriptome analysis of iron-reducing fermentative bacteria
RT Anoxybacter fermentans.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP016379; AZR73201.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3Q9HQK8; -.
DR KEGG; aft:BBF96_07265; -.
DR OrthoDB; 9761531at2; -.
DR Proteomes; UP000267250; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000267250};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 53..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 305..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 351..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 378..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 438..460
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 467..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 499..517
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 537..555
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 567..767
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 815 AA; 95918 MW; EFECE191BA49EDCC CRC64;
MTIEEELWTD WLESRSIFVH YPALAYLIPY LLGIIFWRLC QISWNWWGRE IKVLPYGVFL
ILITLFILRS YWWRFWMLIR ARSFYLFLIF SLFWVGFYYT DYHWKRTEIP NCMRTEAIKV
IGLVWGQKKG KWVIKPDYIY KDDTEKKLPL LKGKIQVLSP NIRIKGQGSL KIGDRVLVKG
ILQPFPSATN PGQFDYQRYQ RYLGFAGQML EPEVYFISRP RFHLLRWMEK VKKKASDFFS
SHLSVINYRL VMALLTGEKD YLEETQLNQF RDLGISHLLA ISGLHLGLVV MWIKKILEWI
RMPKRIWPWV LIVSVWLAVI FVGCQPSALR VGIFITLTQL GQIFQRSNNS FNLLAVTAWL
ILLKNPLALF LLSFQLSFTV YLTILLLYQP MVSWLKFIFP KTLNQLMALS FTAFLGSAPL
ILFHFYRLSF LGILMNLWAV PLIGVILILL LISLLIRLFW PFAGTMLTFI LDYLVGIFNQ
LLGYFTQHFR GIWQPGRPLL IWIYIFYLSL WIFYRLFNFK KLPLYWYQQE KRIVYKFILL
TAIIICLILI FPLSLERLEW VMLDVGQGDG MFLQLPNGFV ILIDGGGELG KENYSGEKVI
KPFLLSRGIR KIDLVCITHF DIDHVRGILP ILEEFDVKRV WAPQGSIEKY AKKVERLVKA
RQIPLYHPVK GQVYKIGNAK IEIFHPEVEQ VYENENDRSL VFRLSYKGIR ILFTGDLGQE
EEKRLVETEW DIKAHFLKVG HHGSRNSTSY SFLKKVEPAF ALISVGENRY GHPAQIILKR
LQREGCQIWR TDKSGAIQVL IQNGQVYIQN FFKLK
//
