ID A0A3Q9I8D5_9BACL Unreviewed; 734 AA.
AC A0A3Q9I8D5;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=PASTA domain-containing protein {ECO:0000313|EMBL:AZS15011.1};
GN ORFNames=EI981_11425 {ECO:0000313|EMBL:AZS15011.1};
OS Paenibacillus lutimineralis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=2707005 {ECO:0000313|EMBL:AZS15011.1, ECO:0000313|Proteomes:UP000270678};
RN [1] {ECO:0000313|Proteomes:UP000270678}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MBLB1234 {ECO:0000313|Proteomes:UP000270678};
RA Nam Y.-D., Kang J., Chung W.-H., Park Y.S.;
RT "Complete genome sequence of Paenibacillus sp. MBLB1234.";
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
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DR EMBL; CP034346; AZS15011.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3Q9I8D5; -.
DR KEGG; plut:EI981_11425; -.
DR OrthoDB; 9804124at2; -.
DR Proteomes; UP000270678; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR CDD; cd06576; PASTA_Pbp2x-like_1; 1.
DR CDD; cd06575; PASTA_Pbp2x-like_2; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005543; PASTA_dom.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03793; PASTA; 2.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SMART; SM00740; PASTA; 2.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
DR SUPFAM; SSF54184; Penicillin-binding protein 2x (pbp-2x), c-terminal domain; 2.
DR PROSITE; PS51178; PASTA; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000270678};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 655..711
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT REGION 708..734
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 720..734
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 734 AA; 81655 MW; A322773E189556DD CRC64;
MIRRLRLRTL VIGGCITFFF IVLMIRVFWL QVMETEFWTA YAEQQWSRKQ TLYATRGTIT
DRNGEVLAMM APAYTVSVNP KLINSLDLQE EVAEGLSEVL GKNKADLIKL VNAKNKEGSF
YVQREVRYEG YRIDQDLSDQ VEVFARNLKD KHELDDVGIY LTKEQKRFYP WKSLAAHVLG
YVDRDGIAIS GLESLYDEEL KGQDGSFEYK SDGRGITVTR ADEIYNPAKN GMNIELTIDH
TIQYYIEEAM KEAFNELKPI SMTVIAADPK TMEILGMANL PTYNPNEYWL EDDLGNFYNH
AIKSVYEPGS TFKIVTLAGA VQEDLFNPKA KYMSGSIRVP GQTLHDIKRS GWGRIDYLEG
VMRSSNVAFV KLGYEMLGPE RLKQYVDNFG FGQKTGIELP GEAAGVVSPE QPSEYATMSY
GHGKLMVTPL QQLAAVGAVA NGGMLLKPHI IKSITDPQSG EVIKTQPEPV RQVISADKAK
EVGEYLEQVV SNSEYGTGRR AYIEGYRIAG KTGTAVKPFK GKYDYTKQVV SFIGYAPVDD
PKVVMLVLID EPKDSDLGGG KAAAPVFQKI MKQMLQYMGV RKTITAPGDS DLAQNTAMLR
TPDLSKLSLQ QALTELRNTD IPYALLGNGK ELVSQFPKPG SSLMKGQQVY LLTEAVNHIK
IPDLKGQSLR DALELLSVLN IYVTFEGEGF VVSQTVLEDS GNKQVKLVLE PPGGVRSESE
EDEEAIDADG EENG
//
