ID A0A3R6F8V2_9BACT Unreviewed; 481 AA.
AC A0A3R6F8V2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 11.
DE SubName: Full=Radical SAM protein {ECO:0000313|EMBL:RHJ83231.1};
GN ORFNames=DW103_07765 {ECO:0000313|EMBL:RHJ83231.1};
OS Parabacteroides sp. AM08-6.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Tannerellaceae;
OC Parabacteroides.
OX NCBI_TaxID=2292053 {ECO:0000313|EMBL:RHJ83231.1, ECO:0000313|Proteomes:UP000285678};
RN [1] {ECO:0000313|EMBL:RHJ83231.1, ECO:0000313|Proteomes:UP000285678}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AM08-6 {ECO:0000313|EMBL:RHJ83231.1,
RC ECO:0000313|Proteomes:UP000285678};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RHJ83231.1}.
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DR EMBL; QRMP01000008; RHJ83231.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3R6F8V2; -.
DR OrthoDB; 9801424at2; -.
DR Proteomes; UP000285678; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR PANTHER; PTHR43409:SF16; RADICAL SAM DOMAIN PROTEIN; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW Reference proteome {ECO:0000313|Proteomes:UP000285678}.
FT DOMAIN 197..430
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 481 AA; 54899 MW; 3898ED8156A92F73 CRC64;
MKITFITPPS LDGYKPAERT AGCTRVVYDM PNIYELTVAA VLEKKGWNVQ YKNFVLAGGT
KEDCFDFLRE DNSDCYFFWT VNLSIPTDKE LQAFIYKQRP EAVSVFLGPG GTYFTSLLLE
NTASIVVRGE PEETVDELIT LLATGSDWRN IKGISYLDSV SGKVINNPAR PLIKNLDELP
FPAIHFIQNY VFSNPKLKVS PYMSVVTSRN CPFHCIYCVP SSLTFAREIE YKKEHEGKKP
PIGFRSPENV VAEIEELAAQ GFRAIGFMDD NFIVTSKRLK VIGEALKKHQ LVWGCQARVD
AINEEIAAML SEYDCRYVDL GVESFNDDIL RYIKKGITEA QIYSAIRLLK KYKVPVKLNI
LIGTSPIETE ETIRDTLRKA KQLKVDQVMF NIVSPFPATE FYELAKENGW IKGGEYTPTD
VQRNSILSYP NLTSEQMERL LFRNNLRFFL SPSFVWRNMR KFSSFHDFRI ALAALKIKLF
G
//
