ID A0A3R6HW01_9FIRM Unreviewed; 511 AA.
AC A0A3R6HW01;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=Sugar transporter {ECO:0000313|EMBL:RHO29430.1};
GN ORFNames=DW183_11645 {ECO:0000313|EMBL:RHO29430.1};
OS Roseburia sp. AM16-25.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX NCBI_TaxID=2292065 {ECO:0000313|EMBL:RHO29430.1, ECO:0000313|Proteomes:UP000286373};
RN [1] {ECO:0000313|EMBL:RHO29430.1, ECO:0000313|Proteomes:UP000286373}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AM16-25 {ECO:0000313|EMBL:RHO29430.1,
RC ECO:0000313|Proteomes:UP000286373};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- SIMILARITY: Belongs to the sodium:galactoside symporter (TC 2.A.2)
CC family. {ECO:0000256|ARBA:ARBA00009617}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RHO29430.1}.
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DR EMBL; QUCW01000006; RHO29430.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3R6HW01; -.
DR Proteomes; UP000286373; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR InterPro; IPR039672; MFS_2.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR11328:SF24; INNER MEMBRANE SYMPORTER YICJ-RELATED; 1.
DR PANTHER; PTHR11328; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13347; MFS_2; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000286373};
KW Sugar transport {ECO:0000313|EMBL:RHO29430.1};
KW Symport {ECO:0000256|ARBA:ARBA00022847};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022847}.
FT TRANSMEM 34..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 100..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 131..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 209..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 308..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 361..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 423..441
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 456..478
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT COILED 482..509
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 511 AA; 55600 MW; 227161D86D42BB4F CRC64;
MEGLTMANEK KAGIFNASAR DGVQYRKASM LEMILGNANN GCGICFYLLM MYASYIANAG
YAIVPAVAGI IITGTRLFDG FTDALFAALF EKMNPKHGKI RIFLVVGWVM AALAVLMMYD
WASGKYTGTT GIVVFILIYV VYICGYTING MAGGTIGIVL TNDPTQRPMM GVFGTLYSYL
VPLIFNNIVT FAILPRYDNQ YNAPMLKEAC YWYVITAGIF MLLACFAVRK SDNAKTFEVI
GKDGQKNQTV KFKDMVAILK DNKPCQMYML TGISDKLAQQ VGSQSIITTM ASGILIGSYA
AATMIGNFTM IVGIVFAFGG GVFVAKMGAK KATTVWSWLS IAVAVVTVVF CAILGPTGMK
SIGVFGVPMI IYALLQLATT GTKMVLTTTG TAMRADIVDY EYARTGNYLP AVISGVYNFI
DKLITSLAST IAAFCITLIG YKDTVPQMGD PATKGVFWMT MFLMFGLPIL GWLCNIVAMR
FYKLNKEEMV EVQKKVAEMK AKAETNENAE A
//
