ID A0A3R6IPT4_9BACT Unreviewed; 928 AA.
AC A0A3R6IPT4;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN Name=uvrA {ECO:0000313|EMBL:RHO72982.1};
GN ORFNames=DW083_08030 {ECO:0000313|EMBL:RHO72982.1};
OS Parabacteroides sp. AF48-14.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Tannerellaceae;
OC Parabacteroides.
OX NCBI_TaxID=2292052 {ECO:0000313|EMBL:RHO72982.1, ECO:0000313|Proteomes:UP000283361};
RN [1] {ECO:0000313|EMBL:RHO72982.1, ECO:0000313|Proteomes:UP000283361}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF48-14 {ECO:0000313|EMBL:RHO72982.1,
RC ECO:0000313|Proteomes:UP000283361};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RHO72982.1}.
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DR EMBL; QUDI01000013; RHO72982.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3R6IPT4; -.
DR Proteomes; UP000283361; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 3.30.190.20; -; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF4; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 589..925
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 928 AA; 103316 MW; B4984772EB294082 CRC64;
MSENNSIFIK GARINNLKNI DVEIPRDKLV VITGLSGSGK SSLAFDTLYA EGQRRYVESL
SAYARQFLGR MSKPECDYIK GIPPAIAIEQ KVNTRNPRST VGTSTEIYEY LRLLYARIGK
TISPVSGMEV KKHQVSDIVK EVLAYPDGTR FAVYAPVVLP EGRGIKEQLE ILQKEGYTRL
SINETIYRIG EVLADEALLS SPAIELLIDR LVVSGDKTLK SRLADSAETA FFEGHDTCII
RIYAPEGTVI KEYSKKFEAD GITFEEPNDM MFSFNNPLGA CPTCEGFGKV LGIDENLVVP
DKSLSVFQGA VVCWKGEVMG EWLREFIAKS EKYNFPIHRP YYDLTQKEKD LLWHGARGLH
GIDDFFKFVE ENLYKIQYRV MQARYRGKTI CPTCKGSRLR PEALYVKVGG KDIAELVTLP
ITEAKAFFDN LQLDENEAAI ARRLLTEITN RLQFLLDVGL GYLTLDRLSA SLSGGESQRI
NLATSLGSSL VGSLYILDEP SIGLHSRDTD LLIKVLRQLQ ALGNTVVVVE HDEEIIRAAD
YIIDIGPKAG RLGGEVVYQG DVNDLRTSSN SYTVRYLTGE DQIEVPAFRR LWNNYIEVKG
ARKNNLKGID VKFPLNVMTV VTGVSGSGKS SLVRDIFYEG VKHYLDDAAR LMVDCSGLEG
DMHLIKGIEF VDQNSIGKSS RSNPVTYIGA YDEIRKLYGD QPLSKQMGYS AAYFSFNKEG
GRCEECKGEG KITVEMQFMA DITLECENCH GKRFKQDVLD VEYHGASIYD MLEMTVNQAI
EFFEQHPGAQ EKKIVKKLKP LQDVGLGYIK LGQTSSTLSG GENQRVKLAY YLGQEKQEPT
LFVFDEPTTG LHFHDIKTLL KAFNALIGKG HTVVIIEHNM DVIKCADYLI DLGPEGGSAG
GSLVCAGTPE EVAMCEASYT GKYLKDKL
//
