ID   A0A3R6UAM2_9FIRM        Unreviewed;       554 AA.
AC   A0A3R6UAM2;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Nucleoside kinase {ECO:0000313|EMBL:RHV64340.1};
GN   ORFNames=DXB15_15820 {ECO:0000313|EMBL:RHV64340.1};
OS   Roseburia sp. OM02-15.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX   NCBI_TaxID=2292368 {ECO:0000313|EMBL:RHV64340.1, ECO:0000313|Proteomes:UP000285983};
RN   [1] {ECO:0000313|EMBL:RHV64340.1, ECO:0000313|Proteomes:UP000285983}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OM02-15 {ECO:0000313|EMBL:RHV64340.1,
RC   ECO:0000313|Proteomes:UP000285983};
RA   Zou Y., Xue W., Luo G.;
RT   "A genome reference for cultivated species of the human gut microbiota.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RHV64340.1}.
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DR   EMBL; QULX01000030; RHV64340.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3R6UAM2; -.
DR   Proteomes; UP000285983; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd02028; UMPK_like; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR006083; PRK/URK.
DR   InterPro; IPR018163; Thr/Ala-tRNA-synth_IIc_edit.
DR   PANTHER; PTHR10285:SF159; PHOSPHORIBULOKINASE _ URIDINE KINASE FAMILY PROTEIN; 1.
DR   PANTHER; PTHR10285; URIDINE KINASE; 1.
DR   Pfam; PF00485; PRK; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF55186; ThrRS/AlaRS common domain; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:RHV64340.1};
KW   Transferase {ECO:0000313|EMBL:RHV64340.1}.
FT   DOMAIN          293..489
FT                   /note="Phosphoribulokinase/uridine kinase"
FT                   /evidence="ECO:0000259|Pfam:PF00485"
SQ   SEQUENCE   554 AA;  64060 MW;  7D52279599C64B33 CRC64;
     MEQKVCSLTI RGETKQYPLD TTFQQIADEY QKQFENKIVL VKFQNDLKEL SQSVLRDGSL
     EFVTADQKPG KDTYRRSLTL LMETAAWKLY PNLELLVQHS IGQGYYCEFR HKDAICVPDW
     KMLSSLKEKM QDFVKADLPI IKYNMNTQDA SARFREMGRM DKVRLMRYRR SSRVNVYELQ
     GFPDYYYGYM VPSTGYLEYF DLLLYQNGFM LMFPGKDPKV VAEFSASDKL FNTLNDSAQW
     GIDMGIRTVG ELNDVIASGR IQDMILVQES YMEQKIGDIA ETIASDRRKK FVLIAGPSSS
     GKTTFSHRLS IQMTAHGLKP HPISLDDFYC NREETPLDEN GEFDFECLEA LDIPLFNQCM
     TDLLAGKEVT LPVFNFKTGH REYRQKPLKM GPDDVLVIEG IHGLNEKLSY ELPKENKYKI
     YISALTQLNI DDHNNLSTAD GRLIRRMVRD ARTRNTTARE TLARWHSVRR GEEKNIFPYQ
     EEADIMFNSA LIYELSVLKL YAEPLLFSID TTCPEYPEAK RLLKFLDYFL PVPGENIGHN
     SILREFIGGS CFHV
//