ID A0A3R7BQ43_9FIRM Unreviewed; 617 AA.
AC A0A3R7BQ43;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 03-MAY-2023, entry version 11.
DE RecName: Full=GP-PDE domain-containing protein {ECO:0000259|PROSITE:PS51704};
GN ORFNames=DXB15_14070 {ECO:0000313|EMBL:RHV65592.1};
OS Roseburia sp. OM02-15.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX NCBI_TaxID=2292368 {ECO:0000313|EMBL:RHV65592.1, ECO:0000313|Proteomes:UP000285983};
RN [1] {ECO:0000313|EMBL:RHV65592.1, ECO:0000313|Proteomes:UP000285983}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OM02-15 {ECO:0000313|EMBL:RHV65592.1,
RC ECO:0000313|Proteomes:UP000285983};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RHV65592.1}.
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DR EMBL; QULX01000020; RHV65592.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3R7BQ43; -.
DR Proteomes; UP000285983; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd08579; GDPD_memb_like; 1.
DR Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR InterPro; IPR018476; GlyceroP-diester-Pdiesterase_M.
DR InterPro; IPR030395; GP_PDE_dom.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR PANTHER; PTHR46211; GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE; 1.
DR PANTHER; PTHR46211:SF8; PHOSPHODIESTERASE-RELATED; 1.
DR Pfam; PF03009; GDPD; 1.
DR Pfam; PF10110; GPDPase_memb; 1.
DR SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR PROSITE; PS51704; GP_PDE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 365..596
FT /note="GP-PDE"
FT /evidence="ECO:0000259|PROSITE:PS51704"
SQ SEQUENCE 617 AA; 70897 MW; E23509C5C3474744 CRC64;
MKKIIRYLRY AFRLLKLNIG TLLVFELLYK FVSMAVFKPL LSGLMKLALK AQGLSYLSDE
TMGTFLKAPL TWVFLVLIVF GMAFFTMFDI CCIICCIHAS FRKQEMPLLA LIRQGFKTSL
RVIYPRNIIM MLYLLIIIPM THALVISGYI TKFTVPQFIV DYIMSHTWLA ILYVGFWVFI
GLRSFHWIYS LHYFCLENCN FKQARKRSFH LQGKHYWRDM AVVVGWSLAC IGIYYGIILF
GSWLVSKVNL ALPTHDLFSS LTLSGISLLM DVCGAIFFCF DLPLFFLCVS LLFYYYKAAS
GEKIPGQFKN LDNAYRLTKT GWAKKLYLYR KRIIAISIVV AIGVNFAYTF ADKRGVLHMG
LDNPVEVTAH RGYSTEYPEN TIPAFKGAIT VGADWAELDV QQTADGEVIV MHDSSLKRTT
GLDKEVWQVT WDEIKNLDNG SWFNKKFQTV RIPTLEEVLK VCRGKIRLNI EIKPSGHDKD
LEEQVAKLLK EYHMRDTCVV SSLKYESLQK VKEADSSIET VYITSVSYGN FTDLEYADGY
SVESTMLSQS FVNRAQKAGK QIYVWTVNSE DQLEKVVGMG IDNVITDDPV MAKELIYKQD
HSTFWDRYVN QLLSIEN
//
