ID A0A3R7GAW4_9STRA Unreviewed; 1142 AA.
AC A0A3R7GAW4;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=VASt domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BBI17_005714 {ECO:0000313|EMBL:RLN44958.1}, BBO99_00005646
GN {ECO:0000313|EMBL:RLN78878.1};
OS Phytophthora kernoviae.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=325452 {ECO:0000313|EMBL:RLN44958.1, ECO:0000313|Proteomes:UP000285883};
RN [1] {ECO:0000313|Proteomes:UP000285624, ECO:0000313|Proteomes:UP000285883}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Chile2 {ECO:0000313|EMBL:RLN44958.1}, and Chile4
RC {ECO:0000313|EMBL:RLN78878.1};
RA Studholme D.J., Sanfuentes E., Panda P., Hill R., Sambles C., Grant M.,
RA Williams N.M., Mcdougal R.L.;
RT "Genome sequencing of oomycete isolates from Chile give support for New
RT Zealand origin for Phytophthora kernoviae and make available the first
RT Nothophytophthora sp. genome.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLN44958.1}.
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DR EMBL; MAYM02000241; RLN44958.1; -; Genomic_DNA.
DR EMBL; MBDN02000170; RLN78878.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3R7GAW4; -.
DR STRING; 325452.A0A3R7GAW4; -.
DR Proteomes; UP000285624; Unassembled WGS sequence.
DR Proteomes; UP000285883; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR CDD; cd00821; PH; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR010482; Peroxin.
DR InterPro; IPR006614; Peroxin/Ferlin.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR031968; VASt.
DR PANTHER; PTHR47666; PROTEIN VASCULAR ASSOCIATED DEATH 1, CHLOROPLASTIC; 1.
DR PANTHER; PTHR47666:SF1; TBC1 DOMAIN FAMILY MEMBER 9B ISOFORM X1; 1.
DR Pfam; PF06398; Pex24p; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF16016; VASt; 2.
DR SMART; SM00694; DysFC; 1.
DR SMART; SM00693; DysFN; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS51778; VAST; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000285624};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 129..230
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 483..667
FT /note="VASt"
FT /evidence="ECO:0000259|PROSITE:PS51778"
FT DOMAIN 684..861
FT /note="VASt"
FT /evidence="ECO:0000259|PROSITE:PS51778"
FT REGION 53..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 868..909
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1033..1065
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..80
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 895..909
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1039..1055
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1142 AA; 126428 MW; FDF386EEB5981CAC CRC64;
METATCAGDD ASSLGGDAHA FLDLLMVVTV GLAVCVVLFR VLFTVFPMPS QVANASSSSS
SSSSSSSPEA SRTTDRGTPV KRSTSVRDRL ERETRTRLPR RSTYYSMPFF ADSVANKQEF
VEGLVELGDA SLDGWLLVKK GLQRGKHWKK RFVVLDVHAR IKYYPNADAA RRNTNVKGSL
AVHAVKPADP FEFGANTLEI RGTLGGTYFF RAEDDMAARS WLCVLTMRAI QGHVPGRIDS
VLSAAVAPTP LQSAATSNGG GIPSLSSSKL HSFSDSGENG FNALSVTASA LNLLSNSGEA
VIPPVRLKSH ALELVVQDMS YDKDASLRQF YVVAKFKSEL HDYSSVPVGQ TSPKPRGEKG
EKGAMVKWNE KLTWHFQDHL CSECQECRSL GATSGAFCGL PDIMVLHVYE IHLRYLTTKI
GEVSLSLREL LGFTGMRTAE FSCAWPVTST RDAILGQLLL SLKYSVDSAG GAELTQFLVT
STDERELVGE YPLHASLTNG YDFFKTFLAD GTSDRLNDYY EERGDSEIEV SEWAASKEFG
GQVRTVSCRS PTNASIGPSH TMLTTTDHVP FVECELDATE KLVMQSKAVM HDIPYGDCFT
VEKVTVVERI PSNDGSPGQL VAKVYLGVPF SKGCMFKSKI ISATREAMVS SSKLYFHVVN
RSVENPSASQ AATPIKPFLV STEEERQPIG EFDLHPAVKD ALHFFDLFYA DNTLSRWQNI
HKEAGDTEHV VGKWEDSAEF GGQVREMKYR AKSTSSLGPA TTMAQQLVHV PFSSQGRDSL
DADRLTVEHK LWLLDIPYGD CFHVETIYVI EPRTDAIGSP LVAKVFVGIP FSKGTMFKSK
IQSVTKEGIV KSAKMVFEGF QKALDAEEST DASESARHSA SANNDGGARG RPRRSSSTGV
ISRRHPNVTR YNSTLDGSVA LEEIFENQRV SMFGKWAPNH LLPTDRPRFS NRDGDKAMSF
EQVSLPPLWS WTTPWRIDKN YTDCDDEGWS YATDFPRFKF HLARGRSSMK RLGASVRRRR
WIRMMAYVPP EASATTDAAS PPLPASNTTR RNRSRGSQEP AGKHLKLVQG KQCYSEQRQA
YRVVFLMAFT VVAVLSWSAE AGGPRPLSDR YEDFRARMLQ QRMAKQAAYE ERERAFFSRK
RH
//
