ID A0A3R7H9W3_9STRA Unreviewed; 661 AA.
AC A0A3R7H9W3;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=guanylate kinase {ECO:0000256|ARBA:ARBA00012961};
DE EC=2.7.4.8 {ECO:0000256|ARBA:ARBA00012961};
GN ORFNames=BBI17_001787 {ECO:0000313|EMBL:RLN38079.1}, BBO99_00001569
GN {ECO:0000313|EMBL:RLN84093.1};
OS Phytophthora kernoviae.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=325452 {ECO:0000313|EMBL:RLN38079.1, ECO:0000313|Proteomes:UP000285883};
RN [1] {ECO:0000313|Proteomes:UP000285624, ECO:0000313|Proteomes:UP000285883}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Chile2 {ECO:0000313|EMBL:RLN38079.1}, and Chile4
RC {ECO:0000313|EMBL:RLN84093.1};
RA Studholme D.J., Sanfuentes E., Panda P., Hill R., Sambles C., Grant M.,
RA Williams N.M., Mcdougal R.L.;
RT "Genome sequencing of oomycete isolates from Chile give support for New
RT Zealand origin for Phytophthora kernoviae and make available the first
RT Nothophytophthora sp. genome.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the guanylate kinase family.
CC {ECO:0000256|ARBA:ARBA00005790}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLN38079.1}.
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DR EMBL; MAYM02000497; RLN38079.1; -; Genomic_DNA.
DR EMBL; MBDN02000023; RLN84093.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3R7H9W3; -.
DR STRING; 325452.A0A3R7H9W3; -.
DR Proteomes; UP000285624; Unassembled WGS sequence.
DR Proteomes; UP000285883; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004385; F:guanylate kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd22973; DD_CATIP; 1.
DR CDD; cd00071; GMPK; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR047501; DD_CATIP.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR008144; Guanylate_kin-like_dom.
DR InterPro; IPR017665; Guanylate_kinase.
DR InterPro; IPR020590; Guanylate_kinase_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR03263; guanyl_kin; 1.
DR PANTHER; PTHR23117:SF13; GUANYLATE KINASE; 1.
DR PANTHER; PTHR23117; GUANYLATE KINASE-RELATED; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00072; GuKc; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF47391; Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS00856; GUANYLATE_KINASE_1; 1.
DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
PE 3: Inferred from homology;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000285624};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT REPEAT 57..89
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 90..122
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 470..652
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
FT REGION 255..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 351..385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 296..313
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 661 AA; 70854 MW; 376DFC7BB4DE877B CRC64;
MFGYFAEKLN VKNLGELLAP TLTPDQELHA AIEQGLYDKF VYILDEQHID PNAKNDAGNL
PIHTAAYYGR VQFLEVLLAH NVDVNATCPR QNSPLHFAAA QSRDDAVKFL VSHGANPATR
NRSGRTPYDV AKGDNIRQYL LPLQFQHEDP AQATSFLPPG ITPSVDPTAP RPVIAPPPTS
GDYNAMQGPP MGMPPQQTAQ TNLYAAATHS AIPRGGPSRF ARKDYRPIQA DGFGSSVGNE
ELTAKFGNKR EIKVTAPPPS LLVPPAPSSV DNEAANGSPS APAPPAAPGV NPYASNYVTK
PRSSSSTSGG YQGYAPPNAG AGASAAARGP PQFKIFNPKL ATNADVSGAA APAPAQVPAP
MAQPPAFGSA APAAPQYPPA QSPHQLTGAM STAEQEATKT LDSLSFEELS LLNERKEALK
KEHAAYVNAH PEIKTLLSGF MSALLLEKPQ DVVAFAAEHF SAFKPPHTEL QPLVIAGPSG
VGKGTLINLL LEKFPSTFGF SVSHTTRGPR EGEVDGVAYH FTAKDKVLKE IEAGLFLEHA
EVHSNVYGTS KRAVLDVQEK GKICILDIDI QGVQQVKKSG IKAKYLFISP PSMEELEKRL
RGRATETEDK IQLRVKNAAG EVEFGQQPGV FDYNLVNKVV NDSLRELLTT LKEWYPSVEL
K
//
