ID A0A3R7I1A1_9STRA Unreviewed; 1085 AA.
AC A0A3R7I1A1;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Transcription elongation factor SPT5 {ECO:0000256|PIRNR:PIRNR036945};
GN ORFNames=BBI17_000854 {ECO:0000313|EMBL:RLN37714.1}, BBO99_00000952
GN {ECO:0000313|EMBL:RLN84899.1}, JM16_000718
GN {ECO:0000313|EMBL:KAG2531675.1};
OS Phytophthora kernoviae.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=325452 {ECO:0000313|EMBL:RLN84899.1, ECO:0000313|Proteomes:UP000285624};
RN [1] {ECO:0000313|EMBL:KAG2531675.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NZFS 2646 {ECO:0000313|EMBL:KAG2531675.1};
RX PubMed=26981359;
RA Studholme D.J., McDougal R.L., Sambles C., Hansen E., Hardy G., Grant M.,
RA Ganley R.J., Williams N.M.;
RT "Genome sequences of six Phytophthora species associated with forests in
RT New Zealand.";
RL Genom Data 7:54-56(2015).
RN [2] {ECO:0000313|Proteomes:UP000285624, ECO:0000313|Proteomes:UP000285883}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Chile2 {ECO:0000313|EMBL:RLN37714.1}, and Chile4
RC {ECO:0000313|EMBL:RLN84899.1};
RA Studholme D.J., Sanfuentes E., Panda P., Hill R., Sambles C., Grant M.,
RA Williams N.M., Mcdougal R.L.;
RT "Genome sequencing of oomycete isolates from Chile give support for New
RT Zealand origin for Phytophthora kernoviae and make available the first
RT Nothophytophthora sp. genome.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAG2531675.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NZFS 2646 {ECO:0000313|EMBL:KAG2531675.1};
RA Studholme D.J.;
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR036945}. Plastid, chloroplast
CC {ECO:0000256|ARBA:ARBA00004229}.
CC -!- SIMILARITY: Belongs to the SPT5 family. {ECO:0000256|ARBA:ARBA00006956,
CC ECO:0000256|PIRNR:PIRNR036945}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLN84899.1}.
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DR EMBL; JPWV03000009; KAG2531675.1; -; Genomic_DNA.
DR EMBL; MAYM02000527; RLN37714.1; -; Genomic_DNA.
DR EMBL; MBDN02000013; RLN84899.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3R7I1A1; -.
DR STRING; 325452.A0A3R7I1A1; -.
DR Proteomes; UP000285624; Unassembled WGS sequence.
DR Proteomes; UP000285883; Unassembled WGS sequence.
DR Proteomes; UP000785171; Unassembled WGS sequence.
DR GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0006354; P:DNA-templated transcription elongation; IEA:InterPro.
DR GO; GO:0032784; P:regulation of DNA-templated transcription elongation; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd06081; KOW_Spt5_1; 1.
DR CDD; cd06082; KOW_Spt5_2; 1.
DR CDD; cd06083; KOW_Spt5_3; 1.
DR CDD; cd06084; KOW_Spt5_4; 1.
DR CDD; cd06085; KOW_Spt5_5; 1.
DR CDD; cd06086; KOW_Spt5_6; 1.
DR CDD; cd09888; NGN_Euk; 1.
DR Gene3D; 2.30.30.30; -; 4.
DR Gene3D; 3.30.70.940; NusG, N-terminal domain; 1.
DR InterPro; IPR005824; KOW.
DR InterPro; IPR041973; KOW_Spt5_1.
DR InterPro; IPR041975; KOW_Spt5_2.
DR InterPro; IPR041976; KOW_Spt5_3.
DR InterPro; IPR041977; KOW_Spt5_4.
DR InterPro; IPR041978; KOW_Spt5_5.
DR InterPro; IPR041980; KOW_Spt5_6.
DR InterPro; IPR005100; NGN-domain.
DR InterPro; IPR036735; NGN_dom_sf.
DR InterPro; IPR039385; NGN_Euk.
DR InterPro; IPR014722; Rib_uL2_dom2.
DR InterPro; IPR039659; SPT5.
DR InterPro; IPR022581; Spt5_N.
DR InterPro; IPR017071; TF_Spt5_eukaryote.
DR InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR PANTHER; PTHR11125; SUPPRESSOR OF TY 5; 1.
DR PANTHER; PTHR11125:SF7; TRANSCRIPTION ELONGATION FACTOR SPT5; 1.
DR Pfam; PF03439; Spt5-NGN; 1.
DR Pfam; PF11942; Spt5_N; 1.
DR PIRSF; PIRSF036945; Spt5; 1.
DR SMART; SM00739; KOW; 7.
DR SUPFAM; SSF50104; Translation proteins SH3-like domain; 3.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Chloroplast {ECO:0000256|ARBA:ARBA00022528};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR036945};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Plastid {ECO:0000256|ARBA:ARBA00022528};
KW Reference proteome {ECO:0000313|Proteomes:UP000285624};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|PIRNR:PIRNR036945}.
FT DOMAIN 250..278
FT /note="KOW"
FT /evidence="ECO:0000259|SMART:SM00739"
FT DOMAIN 403..430
FT /note="KOW"
FT /evidence="ECO:0000259|SMART:SM00739"
FT DOMAIN 458..485
FT /note="KOW"
FT /evidence="ECO:0000259|SMART:SM00739"
FT DOMAIN 585..612
FT /note="KOW"
FT /evidence="ECO:0000259|SMART:SM00739"
FT DOMAIN 674..701
FT /note="KOW"
FT /evidence="ECO:0000259|SMART:SM00739"
FT DOMAIN 984..1011
FT /note="KOW"
FT /evidence="ECO:0000259|SMART:SM00739"
FT DOMAIN 1033..1060
FT /note="KOW"
FT /evidence="ECO:0000259|SMART:SM00739"
FT REGION 1..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 120..139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 805..858
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..34
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 63..81
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..113
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 120..137
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 805..836
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 843..858
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1085 AA; 118405 MW; 2792AA976F508EB9 CRC64;
MSSSEEELDR NLSEDEDVSE DEIPEEEEDE DEEEETPVKK RKAAESKPKP KKRRKPVNKF
IEEEADVDED EEEEEEDDDD FYRSERQMAE EAETGHSYRY EPQDRTKFDE SESAEAIVNR
IKKRHQQSRK QYDGDEEGGD VVQNEVAQQS LLPSIQDPRM WVFKCKPGRE QHLVVALMNK
FIEFARRGEP LMVKSVVASN SKGFIYVEAE REPHAKDSLN GLRDVQQWSM KLVPIHEMTS
VLNVQTRRKP LVAGAWARMK RAGLYKGDLC KVLEILDNGA RAVVKMIPRL DPIVLAGGEQ
PKYKKGQRPP QKLFHANMVP GADVARRRYP STGEMMDTFD NDFYQEGFLI KEVNIATMLT
TEDVSPTLDE INRFSSVAGE DGEHSAEEML ASVETDDWKN KVDLTKGDTV RVIEGDLINL
MGVVLSTNTS NDTVRVMPLH EEIKDTILDF QLKQLMKYVK VGDHIKVVSG MYSGETGTVV
AVDDSEGAPV AIVLVDSMAR EIQVRVRDLQ ESAEISHGLD SYKGKELYDL VALAHGDVGV
ITHVGREGFT VLCQNGQSRT ISDQEVQRKI MSSRTTAALD KKHNHVSVGE MVNVVEGPFS
GHSGTVKHIY RTYLFLHNNR ITTNSGIFVT RARGVILAGS KARSDMISNS TVPRMEAGMR
GQQNQRGGRN QRESELIGQT VKVKKGRWKG YIGIVVDESD QKVKVEIHCK AKIVDIDRLH
ITVAGTRDGS VVDKPRYAGT PMTGATPLPS QTPLHGSAMT PMATPLHRGM ETPQSSGRGG
EAWNVANDDA LLETQMNQEK DITHATSFGT PLEPTAPSSD MSSRYSNPTT PLAPRSPTRD
NMMPVTPAAN PTTPGLNPTT PGLQPRTPAY MMSHNPTTPG MGHEPMGMEP MTPGFNPTTP
GLSAMTPGLN PVTPGLNTPG YNHNPMTPGF GVATPMGGMG RMNSAATPAA TPGMMGGNGV
PMTPAFNQDA SDAAGGSANG EVTWKMKGVE VEVIAGEHNG SVGAITSVSG GSCSIDVDGR
VITVSLNDVR PVVPEKQDTV IILSGDEAGT KGSLIGTDAS DGIVKVDGGS EIKIYAIASL
AKIAQ
//
