ID A0A3R7IEL9_9STRA Unreviewed; 1154 AA.
AC A0A3R7IEL9;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN ORFNames=BBI17_004975 {ECO:0000313|EMBL:RLM97618.1}, BBO99_00004955
GN {ECO:0000313|EMBL:RLN79876.1}, JM16_004472
GN {ECO:0000313|EMBL:KAG2525385.1};
OS Phytophthora kernoviae.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=325452 {ECO:0000313|EMBL:RLM97618.1, ECO:0000313|Proteomes:UP000285883};
RN [1] {ECO:0000313|EMBL:KAG2525385.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NZFS 2646 {ECO:0000313|EMBL:KAG2525385.1};
RX PubMed=26981359;
RA Studholme D.J., McDougal R.L., Sambles C., Hansen E., Hardy G., Grant M.,
RA Ganley R.J., Williams N.M.;
RT "Genome sequences of six Phytophthora species associated with forests in
RT New Zealand.";
RL Genom Data 7:54-56(2015).
RN [2] {ECO:0000313|Proteomes:UP000285624, ECO:0000313|Proteomes:UP000285883}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Chile2 {ECO:0000313|EMBL:RLM97618.1}, and Chile4
RC {ECO:0000313|EMBL:RLN79876.1};
RA Studholme D.J., Sanfuentes E., Panda P., Hill R., Sambles C., Grant M.,
RA Williams N.M., Mcdougal R.L.;
RT "Genome sequencing of oomycete isolates from Chile give support for New
RT Zealand origin for Phytophthora kernoviae and make available the first
RT Nothophytophthora sp. genome.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAG2525385.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NZFS 2646 {ECO:0000313|EMBL:KAG2525385.1};
RA Studholme D.J.;
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLM97618.1}.
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DR EMBL; JPWV03000093; KAG2525385.1; -; Genomic_DNA.
DR EMBL; MAYM02002286; RLM97618.1; -; Genomic_DNA.
DR EMBL; MBDN02000129; RLN79876.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3R7IEL9; -.
DR STRING; 325452.A0A3R7IEL9; -.
DR Proteomes; UP000285624; Unassembled WGS sequence.
DR Proteomes; UP000285883; Unassembled WGS sequence.
DR Proteomes; UP000785171; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR24180:SF42; ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 45; 1.
DR PANTHER; PTHR24180; CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED; 1.
DR Pfam; PF00023; Ank; 2.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF13676; TIR_2; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 7.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 5.
DR PROSITE; PS50088; ANK_REPEAT; 5.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000285624};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 34..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 107..131
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 178..206
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 279..311
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 317..349
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 350..382
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 524..646
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REGION 653..693
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 743..800
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 770..787
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1154 AA; 124818 MW; 037B3800B8DCACC3 CRC64;
MSSTSSNAEP SAVVAPSSSL NDIVKEHQRY EKTYIFTLCE LIVVLEIPYL IYILICIFLP
SSNSGSVVDM LTACDHAAVG IAGPDFATAW YTPRTWKIGG MILIARGQRN PLHVAVAFDQ
IEVVRELLAN GHFDVHQFDN VGVTGSASVG GGGGSGSIAP GLASASHPFG PVGLLQATLL
TPLHVAVTLG HTELTLLLLR YGAKPDEPAL STHPRFTTAP LYWAVDKEST RLLLDAGANP
LALPMPGGSS GLLLTAFEVA RIAGNAAVAR QMEKYGGDVA LTPLHDACAG RRRQEVTFLL
DHGADPNTLG EQVVGCFRRT PLHWAAMRGH ARIMRTLLRY GASVESRDIF GRTPLAWACV
LNRAHAVETL LESGADVDVR DAQGDPLLCI CAAGACASIK RGAKTFAGKR DKLGDDHVQD
DENDIAGDED GGIGDMLSGR RSLARGLDPR IFQMLLDHGV DLQATRASNG DSALHVALRR
RNQAAAVLFV RAGLSLTAVN LLGQRAIDCA RSPALRFAVK KEAGQRDVMI SYSHAHTPLA
CKLRDALERA RVTTWIDSMG PTGITGGSVW RQEIARGIQS SALVLAVLTK DYPQSQWCMK
ELAFAKMQNV PVVAIQCEDM EISEELQVYL WTRQVIDFRP AIKQHYAINT IPSIPYSPSD
SRNDTDDDAR ADSRTASNSS HTMIDTDSRE GETGEVDAIS NMAGKRIASS LELVPDYNDD
AFRHCLRMLL DGIQDQIEEH RARLARRQEQ QQQQSLLPGG EAGGNTAVDN DRVRSRRESR
GNVSECTPEE NDKACAAAEQ SECEDQPAQI NFPEGPLNMP LFRPLRRIES LASSLAFASL
ADTDAYIFIA HGDFHHSFCL RLQKALLKQN IRCVVDQTVP AVQYAHQSES AASTDGIQVQ
SDGFDAAFRG VNQPVTRLPV QTRQLAAKDA ILSCSAVLVV LSPLSANCDL LADQLAFAED
RGKLLVPVLL SLHNVDLAKR YTFSRSLVHH FNTSLGFEQS VEQLSNYLRV QQQSEARQRR
LERRQQDQGD FSARSGPIAV LSPISSVSSA ESRLSSLAAY TDVIEVQSPF DDVLLNSTDS
SLLLPTLPAH IPALEATAGA NPMSLIVMTH KYSSRAISIL KALATSTTGH EPSQMPPLRA
LAAGGVEAEK AAAI
//
