ID A0A3R7J5P6_9STRA Unreviewed; 1051 AA.
AC A0A3R7J5P6;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Elongation factor 2 {ECO:0000256|ARBA:ARBA00017891};
GN ORFNames=BBI17_009142 {ECO:0000313|EMBL:RLN06496.1}, BBO99_00009130
GN {ECO:0000313|EMBL:RLN74024.1}, JM16_008988
GN {ECO:0000313|EMBL:KAG2507364.1}, JM18_009028
GN {ECO:0000313|EMBL:KAG2509912.1};
OS Phytophthora kernoviae.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=325452 {ECO:0000313|EMBL:RLN06496.1, ECO:0000313|Proteomes:UP000285883};
RN [1] {ECO:0000313|EMBL:KAG2507364.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NZFS 2646 {ECO:0000313|EMBL:KAG2507364.1}, and NZFS 3630
RC {ECO:0000313|EMBL:KAG2509912.1};
RX PubMed=26981359;
RA Studholme D.J., McDougal R.L., Sambles C., Hansen E., Hardy G., Grant M.,
RA Ganley R.J., Williams N.M.;
RT "Genome sequences of six Phytophthora species associated with forests in
RT New Zealand.";
RL Genom Data 7:54-56(2015).
RN [2] {ECO:0000313|Proteomes:UP000285624, ECO:0000313|Proteomes:UP000285883}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Chile2 {ECO:0000313|EMBL:RLN06496.1}, and Chile4
RC {ECO:0000313|EMBL:RLN74024.1};
RA Studholme D.J., Sanfuentes E., Panda P., Hill R., Sambles C., Grant M.,
RA Williams N.M., Mcdougal R.L.;
RT "Genome sequencing of oomycete isolates from Chile give support for New
RT Zealand origin for Phytophthora kernoviae and make available the first
RT Nothophytophthora sp. genome.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAG2507364.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NZFS 2646 {ECO:0000313|EMBL:KAG2507364.1}, and NZFS 3630
RC {ECO:0000313|EMBL:KAG2509912.1};
RA Studholme D.J.;
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyzes the GTP-dependent ribosomal translocation step
CC during translation elongation. During this step, the ribosome changes
CC from the pre-translocational (PRE) to the post-translocational (POST)
CC state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound
CC deacylated tRNA move to the P and E sites, respectively. Catalyzes the
CC coordinated movement of the two tRNA molecules, the mRNA and
CC conformational changes in the ribosome.
CC {ECO:0000256|ARBA:ARBA00024731}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLN06496.1}.
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DR EMBL; JPWV03000615; KAG2507364.1; -; Genomic_DNA.
DR EMBL; JPWU03000635; KAG2509912.1; -; Genomic_DNA.
DR EMBL; MAYM02001953; RLN06496.1; -; Genomic_DNA.
DR EMBL; MBDN02000624; RLN74024.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3R7J5P6; -.
DR STRING; 325452.A0A3R7J5P6; -.
DR Proteomes; UP000285624; Unassembled WGS sequence.
DR Proteomes; UP000285883; Unassembled WGS sequence.
DR Proteomes; UP000785171; Unassembled WGS sequence.
DR Proteomes; UP000792063; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd01681; aeEF2_snRNP_like_IV; 1.
DR CDD; cd04096; eEF2_snRNP_like_C; 1.
DR CDD; cd01885; EF2; 1.
DR CDD; cd16268; EF2_II; 1.
DR CDD; cd16261; EF2_snRNP_III; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 3.90.1430.10; Yeast translation eEF2 (G' domain); 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42908:SF3; ELONGATION FACTOR-LIKE GTPASE 1; 1.
DR PANTHER; PTHR42908; TRANSLATION ELONGATION FACTOR-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF03764; EFG_IV; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000285624}.
FT DOMAIN 18..280
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 1051 AA; 116973 MW; A3DB81BDE4438F39 CRC64;
MATRATPELL GSLQHAPERI RNICILAHVD HGKTTLSDSL VSSNGIISER LAGKVRYLDN
TEEEQIRGIT MKSSAISLVY QPEPITDKES EAPYLINLVD SPGHVDFSFD VSTAVRLCDG
ALVLIDAVEG VCAQTHAVIR QAWKEGIRPC LVINKMDRLI FELQFSPMEA YQRLNRILEQ
ANAVLSSMIR MDVLEKYDQE DTSEEKKEVE ESVDGDEVST DKIEITLDDE AISKVTEQLE
NEMLFSPANG NVIFASATDG WAFGIGYFAS LYAKKLELPV RVMRQALWGE YYYNGKTKKI
VTKPPTSNSQ TMFCSFILDL VWSAYTTLTK PVGSDADLES LRKLTRQLRV ARLVTDRELK
QSDRKNAIQA VMRKWLPLST TVLKMVTRVL PSPVTAQVKR AEKLCTISSE QLDKSPQHAR
VFRSLQACET SEEAPLVIYI CKVISVEANV LSDYHQAGLA ANDEVYVGVG RVYSGVLRAG
QPLYVLDPKF QGISGEVDVD TVDPSTVKHI TRIDNGLIKT YMIMGRDLLK LDRVPAGNIV
GIVGLQEHVL KTATLSSTLA CPSLTKMPYQ AKPIVRVAVE PEDPRNFGAL EAGLQRLYRS
DPTVEVHVQE TGEHVIVALG ELHLERCIKD LKDRFAKVAV QVSEPLVGFR ESIVDGTISS
FQENIVFKDL LTPDVPKEDQ IDKEASASTD ADPKVALGTT PDGSLTLKLR ALPLPLETAQ
LLEESAVLLK RIVHSKKTTG DEINIKELVV DAGAEEISAF KKKLEKSLQK SENSFLKTLP
LDKIWSCGPR RVGPNILINN IPDYCASGRL FPSDSTTEIS VSNSEKAGAI KKMENSIVTG
FQMTSSAGPL CDEPVWGVAF IIEDVTFHEK ESEENKEEEQ AEVSKYGPLS GQVISIMRTT
CLMSFVKQSV RLVEAVYECT VQCQAEQLGK LYSVISKRRG DIYSEELSDG TALFTVKAHL
PVVESFGFAT DLLIQTSGAA SNPQLIFSHW SIIDMDPFFQ PQTEEEREDY GERVYEHNYV
RRYIEAVRKR KGLSRDEKIV VHAEKQRTLK R
//
