ID A0A3R7JB70_9STRA Unreviewed; 1214 AA.
AC A0A3R7JB70;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Bile salt export pump {ECO:0008006|Google:ProtNLM};
GN ORFNames=BBI17_001206 {ECO:0000313|EMBL:RLN43844.1}, BBO99_00001481
GN {ECO:0000313|EMBL:RLN84277.1}, JM16_002153
GN {ECO:0000313|EMBL:KAG2529133.1}, JM18_001267
GN {ECO:0000313|EMBL:KAG2532360.1};
OS Phytophthora kernoviae.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=325452 {ECO:0000313|EMBL:RLN84277.1, ECO:0000313|Proteomes:UP000285624};
RN [1] {ECO:0000313|EMBL:KAG2529133.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NZFS 2646 {ECO:0000313|EMBL:KAG2529133.1}, and NZFS 3630
RC {ECO:0000313|EMBL:KAG2532360.1};
RX PubMed=26981359;
RA Studholme D.J., McDougal R.L., Sambles C., Hansen E., Hardy G., Grant M.,
RA Ganley R.J., Williams N.M.;
RT "Genome sequences of six Phytophthora species associated with forests in
RT New Zealand.";
RL Genom Data 7:54-56(2015).
RN [2] {ECO:0000313|Proteomes:UP000285624, ECO:0000313|Proteomes:UP000285883}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Chile2 {ECO:0000313|EMBL:RLN43844.1}, and Chile4
RC {ECO:0000313|EMBL:RLN84277.1};
RA Studholme D.J., Sanfuentes E., Panda P., Hill R., Sambles C., Grant M.,
RA Williams N.M., Mcdougal R.L.;
RT "Genome sequencing of oomycete isolates from Chile give support for New
RT Zealand origin for Phytophthora kernoviae and make available the first
RT Nothophytophthora sp. genome.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAG2529133.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NZFS 2646 {ECO:0000313|EMBL:KAG2529133.1}, and NZFS 3630
RC {ECO:0000313|EMBL:KAG2532360.1};
RA Studholme D.J.;
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLN84277.1}.
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DR EMBL; JPWV03000032; KAG2529133.1; -; Genomic_DNA.
DR EMBL; JPWU03000011; KAG2532360.1; -; Genomic_DNA.
DR EMBL; MAYM02000340; RLN43844.1; -; Genomic_DNA.
DR EMBL; MBDN02000021; RLN84277.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3R7JB70; -.
DR STRING; 325452.A0A3R7JB70; -.
DR Proteomes; UP000285624; Unassembled WGS sequence.
DR Proteomes; UP000285883; Unassembled WGS sequence.
DR Proteomes; UP000785171; Unassembled WGS sequence.
DR Proteomes; UP000792063; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd18577; ABC_6TM_Pgp_ABCB1_D1_like; 1.
DR CDD; cd18578; ABC_6TM_Pgp_ABCB1_D2_like; 1.
DR CDD; cd03249; ABC_MTABC3_MDL1_MDL2; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR43394:SF11; ALPHA-FACTOR-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR43394; ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL; 1.
DR Pfam; PF00664; ABC_membrane; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50929; ABC_TM1F; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000285624};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 74..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 121..141
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 220..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 299..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 711..739
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 759..779
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 77..362
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 398..635
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 713..1011
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 1046..1211
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 663..684
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1214 AA; 132532 MW; EB806EC62616739B CRC64;
MPTLADKDSH SAVPFAQLLT PRGSHEPGVA HAFKVNQDVD SDADKNNPPG YAATKETYFS
FLDLYRFATF SDRVLLVVGV IMAAVNGALF PCIALVFGEA IDAFAQTVGG VDRDALNQAS
LYYFLIAIGL FVTDYLAYLF FSLSAERQMK ALRAHALKHM LFMDISWYDL HDSLQLSSRI
TGDTVKIKDG MGQKLGDGVK YMCQFIVGYI IGFARGWDIT LVMTCIMPVM GWSMTFVLKR
WRSRATYAQQ VYAEAGAVAE ETLGSIRTVS SLTAEHRALA KYNKHTAVVE KGNIEQSKIL
AVVLGLARCC EWLMYAAGLW YGGSKVWRGE SSPKKVFQAL MGILMGMRSL GLISPNLMAV
IEAKGAAVAL YELLDTQSQI NASDEEQGII PESCSGLIEA INIDFAYPSR PDAPILRDYS
VTIEAGQTVA FVGASGGGKS TIISLLERFY DPKHGSILLD GRDLRTLNIK WLRSQIGLVS
QEPVLFATTI ADNIAAGANF TREDIIAAAK LANAHSFILS LPKDYDTLVG EKGVSLSGGQ
KQRVAIARAI IRQPKILVLD EATSALDAES ERVVQDALND LMSKTNMTTL VIAHRLSTIR
HADKIMVLAD GHIVEEGPHD ELVDIEHGVY QNLYTIQKVK AQEEAEAMAL VLAREKTEQM
ESALIRRSSL SSDETRSSDQ ADDNISVAKH ENVRGFTVWD ANALSKPERG YFIMALVGSA
INGASFPVSA VLMSQLVAIM TIDYAYYQEN DDLSYLSSLP HKVAIYGSIY IAGSVVLLVG
RTLQSYGFQY VAEKLTARLR GVHFSSLCRQ NIGFFDETEH ATGALTANLA TNALRVAMIS
GEAQGRLFQA VFTTVVALLI SFLSGSWLLT LFMLAITPFL VLGDVFRSKN TRGKSILADD
MADVGAHASE VLGSIRTVVS LGLERSACEK FAMLLDEPMK SGERDAQVNG LTVGFSSFIV
YATYAFSFWY GGRLVDEGSI TFLQLMRSLM AIIMSSQSVG ASVGYLADAD NAFEAGGAIL
SLRDRHLTID SFQEDGLRPT EVVGKIEFKN VLFRYPTRPK VTVLKNYNLT IEAGETVAFC
GQSGGGKSTC VALLERFYDP IQGQVLLDGV DIRELNKQRI AIARAIIKYP SILLLDEATS
ALDSESEKIV QEALDKVVAM HRRTTIIIAH RLSTIRKADK ICVMSGGKIA EQGTHQELIS
CHGIYAKLVE TASS
//
