ID A0A3R7K4S7_9STRA Unreviewed; 868 AA.
AC A0A3R7K4S7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN ORFNames=BBI17_003930 {ECO:0000313|EMBL:RLN15008.1}, BBO99_00003906
GN {ECO:0000313|EMBL:RLN81193.1}, JM16_003545
GN {ECO:0000313|EMBL:KAG2521519.1}, JM18_008676
GN {ECO:0000313|EMBL:KAG2511611.1};
OS Phytophthora kernoviae.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=325452 {ECO:0000313|EMBL:RLN15008.1, ECO:0000313|Proteomes:UP000285883};
RN [1] {ECO:0000313|EMBL:KAG2511611.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NZFS 2646 {ECO:0000313|EMBL:KAG2521519.1}, and NZFS 3630
RC {ECO:0000313|EMBL:KAG2511611.1};
RX PubMed=26981359;
RA Studholme D.J., McDougal R.L., Sambles C., Hansen E., Hardy G., Grant M.,
RA Ganley R.J., Williams N.M.;
RT "Genome sequences of six Phytophthora species associated with forests in
RT New Zealand.";
RL Genom Data 7:54-56(2015).
RN [2] {ECO:0000313|Proteomes:UP000285624, ECO:0000313|Proteomes:UP000285883}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Chile2 {ECO:0000313|EMBL:RLN15008.1}, and Chile4
RC {ECO:0000313|EMBL:RLN81193.1};
RA Studholme D.J., Sanfuentes E., Panda P., Hill R., Sambles C., Grant M.,
RA Williams N.M., Mcdougal R.L.;
RT "Genome sequencing of oomycete isolates from Chile give support for New
RT Zealand origin for Phytophthora kernoviae and make available the first
RT Nothophytophthora sp. genome.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAG2511611.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NZFS 2646 {ECO:0000313|EMBL:KAG2521519.1}, and NZFS 3630
RC {ECO:0000313|EMBL:KAG2511611.1};
RA Studholme D.J.;
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Essential component of the vacuolar proton pump (V-ATPase), a
CC multimeric enzyme that catalyzes the translocation of protons across
CC the membranes. Required for assembly and activity of the V-ATPase.
CC {ECO:0000256|RuleBase:RU361189}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00009904, ECO:0000256|RuleBase:RU361189}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLN15008.1}.
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DR EMBL; JPWU03000534; KAG2511611.1; -; Genomic_DNA.
DR EMBL; JPWV03000196; KAG2521519.1; -; Genomic_DNA.
DR EMBL; MAYM02001513; RLN15008.1; -; Genomic_DNA.
DR EMBL; MBDN02000086; RLN81193.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3R7K4S7; -.
DR STRING; 325452.A0A3R7K4S7; -.
DR Proteomes; UP000285624; Unassembled WGS sequence.
DR Proteomes; UP000285883; Unassembled WGS sequence.
DR Proteomes; UP000785171; Unassembled WGS sequence.
DR Proteomes; UP000792063; Unassembled WGS sequence.
DR GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR InterPro; IPR002490; V-ATPase_116kDa_su.
DR InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR PANTHER; PTHR11629:SF63; V-TYPE PROTON ATPASE SUBUNIT A; 1.
DR PANTHER; PTHR11629; VACUOLAR PROTON ATPASES; 1.
DR Pfam; PF01496; V_ATPase_I; 1.
DR PIRSF; PIRSF001293; ATP6V0A1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrogen ion transport {ECO:0000256|ARBA:ARBA00022781,
KW ECO:0000256|RuleBase:RU361189};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|RuleBase:RU361189};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361189};
KW Reference proteome {ECO:0000313|Proteomes:UP000285624};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361189};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361189};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361189}.
FT TRANSMEM 427..451
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 472..489
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 569..587
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 599..622
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 681..700
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 802..827
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT COILED 99..133
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 868 AA; 98955 MW; 42D1C026EFBC6701 CRC64;
MKWLRSAEME YISLIVNEDA AHDCVQKLGD LGVLEFTDLN PELTPFQRRY VNYVKRCDEM
ERKLRYFEVE LTKFNISPKP AGSIDQFLAG NADIRYGSQD TATRALDTME RLLEDKEQEL
LQLNSMHEKL TREYNERKEL QEIISRAGEF FEIEIPEVQV RRTSRTGSRS GGYSFVDSLS
GTGEDAASLR FRNVTGVVPA DERLKFERMV FRTTRGNCFT RFSPIEEPLV DPTNGQPVTK
HAFVIFFQST FIETKLRKIC DAFHARLYSL PSMDDRAAIA HLIQSNAGEL NQSSHILRRN
RESCVLLCRD LAETLESWKW SVLQEKATYH ALNMFRADVS GMLRAEGWVI KEALSSVRRA
VTRAHTAADD KSMPSLVDTV AKPWPAPPTY FETNKFTDAF QSFVETYGCP RYREVNPSVF
TAVTFPFLFG VMYGDIGHGF CVLLFGLYLI LTERRLEQPG LGEMAASIYG GRYMLFMMGA
FAIYAGIIYN DFFSLPLNLF GSKFAYPDCL ESHDREAKCV AEYMIDGKTT YVNATDVSSG
ANVYAMGLDP IWKTSENELL FFNSFKMKVS VIFGIVQMTF GIFLKGWNNL YFRDYSTFLF
EFVPQIVFAC SLFVYMIILI VMKWSIDWTE RMKHEVCPYN YAGEHTGCRP PSLVNTLINI
ALAPGNVVDP LYEGQLETQQ TLLFMGFMSV PAMLLIKPIY LKFQHDRSAP PTSHHVDFDD
EAEERLVSHH HGNSGGGHGG HGEEFEFGEV VIHQGIETIE FVLGMVSNTA SYLRLWALSL
AHSELATVFW EKTMLSTINS DSFIAIFIGF AVFAATTFGV ILAMDVLECF LHALRLHWVE
FQNKFYKADG YKFHPFSFKQ TIKDSQQV
//
