ID A0A3R7M1E5_PENVA Unreviewed; 1036 AA.
AC A0A3R7M1E5;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Putative E3 ubiquitin-protein ligase HERC2 {ECO:0000313|EMBL:ROT64593.1};
GN ORFNames=C7M84_017464 {ECO:0000313|EMBL:ROT64593.1};
OS Penaeus vannamei (Whiteleg shrimp) (Litopenaeus vannamei).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC Malacostraca; Eumalacostraca; Eucarida; Decapoda; Dendrobranchiata;
OC Penaeoidea; Penaeidae; Penaeus.
OX NCBI_TaxID=6689 {ECO:0000313|EMBL:ROT64593.1, ECO:0000313|Proteomes:UP000283509};
RN [1] {ECO:0000313|EMBL:ROT64593.1, ECO:0000313|Proteomes:UP000283509}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Muscle {ECO:0000313|EMBL:ROT64593.1};
RA Zhang X., Yuan J., Li F., Xiang J.;
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ROT64593.1, ECO:0000313|Proteomes:UP000283509}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Muscle {ECO:0000313|EMBL:ROT64593.1};
RA Sun Y., Gao Y., Yu Y.;
RT "The decoding of complex shrimp genome reveals the adaptation for benthos
RT swimmer, frequently molting mechanism and breeding impact on genome.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ROT64593.1}.
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DR EMBL; QCYY01003225; ROT64593.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3R7M1E5; -.
DR STRING; 6689.A0A3R7M1E5; -.
DR EnsemblMetazoa; XM_027373987.1; XP_027229788.1; LOC113821475.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000283509; Unassembled WGS sequence.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd08664; APC10-HERC2; 1.
DR Gene3D; 2.30.30.30; -; 1.
DR Gene3D; 3.30.60.90; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.130.10.30; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; 1.
DR InterPro; IPR004939; APC_su10/DOC_dom.
DR InterPro; IPR021097; CPH_domain.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR037976; HERC2_APC10.
DR InterPro; IPR009091; RCC1/BLIP-II.
DR InterPro; IPR000408; Reg_chr_condens.
DR InterPro; IPR014722; Rib_uL2_dom2.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR PANTHER; PTHR22870; REGULATOR OF CHROMOSOME CONDENSATION; 1.
DR PANTHER; PTHR22870:SF437; X-LINKED RETINITIS PIGMENTOSA GTPASE REGULATOR-RELATED; 1.
DR Pfam; PF03256; ANAPC10; 1.
DR Pfam; PF11515; Cul7; 1.
DR Pfam; PF00415; RCC1; 6.
DR Pfam; PF00569; ZZ; 1.
DR PRINTS; PR00633; RCCNDNSATION.
DR SMART; SM01337; APC10; 1.
DR SMART; SM00291; ZnF_ZZ; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF50985; RCC1/BLIP-II; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS51284; DOC; 1.
DR PROSITE; PS00626; RCC1_2; 1.
DR PROSITE; PS50012; RCC1_3; 7.
DR PROSITE; PS50135; ZF_ZZ_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000283509};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00228}.
FT DOMAIN 234..285
FT /note="ZZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50135"
FT DOMAIN 292..469
FT /note="DOC"
FT /evidence="ECO:0000259|PROSITE:PS51284"
FT REPEAT 489..540
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 541..594
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 595..646
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 647..698
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 701..752
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 753..805
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 806..857
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REGION 47..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1036 AA; 111934 MW; F735D75C0818A583 CRC64;
MEMGFARKSV EHAIKALGGL GTEVTPSPES LVLWLIEHAD LTLSDSDSAP DVLDSDADSL
TDEFNDEPPL LESSPVVEVY RKRSEFTSND EYAMYVRDHI CPGMTVRCCR TYEEVHEGDI
GRVVRVDRGS LHNLNVQVDW QRKGGTYWVR YIHSELLDQP PPPLAASGPI RVGDRVRVKS
SVNTPKYKWG SVNHRSIGVV TSVSTNGQDL IVDFPQQPNW QGLVSEMEVV PSCHMNVTCD
GCGVSPITGA RLKCKVCDNF DYCEECYQTK RSHRHLFNRI AEPGSPAVYA GPPGRGRFRK
KEGILGGADG TIEDWYRCVR NLSVSSRENW AHRLIDGTGS YWQSCGQEGK HWIHLEMQPN
IGIEWLRMLV DPADSSYMPT LVVISGGDSL AKMRELATIR ITPSDTWVTL LRNVKEYMKY
IEIGIKQCKS GGIDCRVHGL AIMGKLVDEF GDPASTVSFL ASDNEDVEDE ITEMTRKSLT
STICFDGEPK VLVWGLNDKD QLGGLKGSKV KMPVLSETLS SLHPVHVAGG SKSLFVVSQE
GKVYACGEGT GGRLGLGHCN NITVPRQITA LSQYVVKKVA VHSGGRHAMA LTVDGKIFSW
GEGEDGKLGH GNRTSYDKPK LIESLKSKRI RDIACGSSHS AAITSSGELY CWGLGEYGRL
GLGDTTTQLK PKLVKALHGQ RVVQVACGSR DAQTLALTSE GMVYSWGDGD FGKLGRGGSE
GCSLPQNIER LNGLGVCQIE CGAQFSLVLT KAGQVWTWGK GDYFRLGHGT DQHVRRPTMV
EGLRARKMLV HVAVGALHCL AVTEAGQVYA WGDNDHGQQG NGTTIVNRRP ALVCGLEGVR
VARVACGSSH SVAWTAPDPP LPAATEPVMF TTTKDPLGAH ALGVVEPLGG DTVTNSNSPG
SSGGSPINPS LSRVVLTLES SAARQAALQH ILNALQVMFA RDCVIAALDS TAAALSQTKE
ELHACEVVTK ISGLQTPESM TDAIAETSSS LSSPNGGEIA EGGAGLCTLY WVLILKSLKT
FSLGYEYSCS YSDNKG
//
