ID A0A3R7NZD9_PENVA Unreviewed; 564 AA.
AC A0A3R7NZD9;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Putative low-density lipoprotein receptor-related protein 2-like {ECO:0000313|EMBL:ROT71109.1};
GN ORFNames=C7M84_010576 {ECO:0000313|EMBL:ROT71109.1};
OS Penaeus vannamei (Whiteleg shrimp) (Litopenaeus vannamei).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC Malacostraca; Eumalacostraca; Eucarida; Decapoda; Dendrobranchiata;
OC Penaeoidea; Penaeidae; Penaeus.
OX NCBI_TaxID=6689 {ECO:0000313|EMBL:ROT71109.1, ECO:0000313|Proteomes:UP000283509};
RN [1] {ECO:0000313|EMBL:ROT71109.1, ECO:0000313|Proteomes:UP000283509}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Muscle {ECO:0000313|EMBL:ROT71109.1};
RA Zhang X., Yuan J., Li F., Xiang J.;
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ROT71109.1, ECO:0000313|Proteomes:UP000283509}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Muscle {ECO:0000313|EMBL:ROT71109.1};
RA Sun Y., Gao Y., Yu Y.;
RT "The decoding of complex shrimp genome reveals the adaptation for benthos
RT swimmer, frequently molting mechanism and breeding impact on genome.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ROT71109.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QCYY01002342; ROT71109.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3R7NZD9; -.
DR Proteomes; UP000283509; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005230; F:extracellular ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR CDD; cd00112; LDLa; 1.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 1.
DR Gene3D; 2.70.170.10; Neurotransmitter-gated ion-channel ligand-binding domain; 1.
DR Gene3D; 1.20.58.390; Neurotransmitter-gated ion-channel transmembrane domain; 1.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR InterPro; IPR006202; Neur_chan_lig-bd.
DR InterPro; IPR036734; Neur_chan_lig-bd_sf.
DR InterPro; IPR006201; Neur_channel.
DR InterPro; IPR038050; Neuro_actylchol_rec.
DR InterPro; IPR018000; Neurotransmitter_ion_chnl_CS.
DR PANTHER; PTHR18945; NEUROTRANSMITTER GATED ION CHANNEL; 1.
DR PANTHER; PTHR18945:SF943; NICOTINIC ACETYLCHOLINE RECEPTOR BETA 3 (DBETA3) SUBUNIT; 1.
DR Pfam; PF00057; Ldl_recept_a; 1.
DR Pfam; PF02931; Neur_chan_LBD; 1.
DR SMART; SM00192; LDLa; 1.
DR SUPFAM; SSF57424; LDL receptor-like module; 1.
DR SUPFAM; SSF63712; Nicotinic receptor ligand binding domain-like; 1.
DR PROSITE; PS50068; LDLRA_2; 1.
DR PROSITE; PS00236; NEUROTR_ION_CHANNEL; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; Lipoprotein {ECO:0000313|EMBL:ROT71109.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Receptor {ECO:0000313|EMBL:ROT71109.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000283509}.
FT DOMAIN 163..314
FT /note="Neurotransmitter-gated ion-channel ligand-binding"
FT /evidence="ECO:0000259|Pfam:PF02931"
FT REGION 458..482
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 502..547
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..524
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 525..547
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 114..126
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 121..139
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
SQ SEQUENCE 564 AA; 63494 MW; 725FD74EDEB9C07F CRC64;
MIIVKSEFLF YTLTVHCHFE LHDFVCKVPK TLTFELRADE DLSLDKTFFL VPLQHRARFL
SVSGRQILVN RTSLSLRSPL GEEVWVAPFT GKQPVGRYQW RGGMGRRNMS LTCCREDEFT
CSTGICVALS RRCDGIEDCA DGSDEWCSLL TPLPRTYRRE QPHGPLTQLN LTVVQLEILE
VDEYGNRFKV KAELHTSWHD DRIRFSQMSR MPSDNILPRG RLWTPRYKLS NAFFEDQQSH
LRKEDVGVIL RAHRDGAGRV VTRGGFEGEV GGLRTRRRDD AHLELTEVFV ASFACHFRLK
DFPFDVHVCR VNISLILNGR SFKAAYSLVD VSHLPPPLEL PLFQSSEVCV LRLRDEDNLT
TGVSFMFLLR RLRGSYALTT FGPCVVLNTI GGLTQFFERD NFSDRIMVTL SCLIVVANLF
SQVATTSPSS ATPKAVEFLF FAVTLRLSWS SLTTLSSAGS ERGAAGRGGG GKERRGRPTY
PLVGKTDVLS VPAVYRPPEV GFPTTSWTAA ENKREHRTTG RTPVKQKTKD GSSCTGSDRS
SLPVTQSSMS SSCLSASWWI RRRL
//
