ID   A0A3R7P236_PENVA        Unreviewed;       440 AA.
AC   A0A3R7P236;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=Tumor susceptibility protein 101 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=C7M84_008294 {ECO:0000313|EMBL:ROT73274.1};
OS   Penaeus vannamei (Whiteleg shrimp) (Litopenaeus vannamei).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC   Malacostraca; Eumalacostraca; Eucarida; Decapoda; Dendrobranchiata;
OC   Penaeoidea; Penaeidae; Penaeus.
OX   NCBI_TaxID=6689 {ECO:0000313|EMBL:ROT73274.1, ECO:0000313|Proteomes:UP000283509};
RN   [1] {ECO:0000313|EMBL:ROT73274.1, ECO:0000313|Proteomes:UP000283509}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Muscle {ECO:0000313|EMBL:ROT73274.1};
RA   Zhang X., Yuan J., Li F., Xiang J.;
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ROT73274.1, ECO:0000313|Proteomes:UP000283509}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Muscle {ECO:0000313|EMBL:ROT73274.1};
RA   Sun Y., Gao Y., Yu Y.;
RT   "The decoding of complex shrimp genome reveals the adaptation for benthos
RT   swimmer, frequently molting mechanism and breeding impact on genome.";
RL   Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family. UEV
CC       subfamily. {ECO:0000256|ARBA:ARBA00009594}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ROT73274.1}.
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DR   EMBL; QCYY01002044; ROT73274.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3R7P236; -.
DR   STRING; 6689.A0A3R7P236; -.
DR   Proteomes; UP000283509; Unassembled WGS sequence.
DR   GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR   GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR   Gene3D; 6.10.140.820; -; 1.
DR   Gene3D; 6.10.250.370; -; 1.
DR   Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR   InterPro; IPR037202; ESCRT_assembly_dom.
DR   InterPro; IPR017916; SB_dom.
DR   InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR   InterPro; IPR008883; UEV_N.
DR   PANTHER; PTHR23306:SF3; TUMOR SUPPRESSOR PROTEIN 101; 1.
DR   PANTHER; PTHR23306; TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED; 1.
DR   Pfam; PF05743; UEV; 1.
DR   Pfam; PF09454; Vps23_core; 1.
DR   SUPFAM; SSF140111; Endosomal sorting complex assembly domain; 1.
DR   SUPFAM; SSF54495; UBC-like; 1.
DR   PROSITE; PS51312; SB; 1.
DR   PROSITE; PS51322; UEV; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Endosome {ECO:0000256|ARBA:ARBA00022753};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Reference proteome {ECO:0000313|Proteomes:UP000283509};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          5..148
FT                   /note="UEV"
FT                   /evidence="ECO:0000259|PROSITE:PS51322"
FT   DOMAIN          374..440
FT                   /note="SB"
FT                   /evidence="ECO:0000259|PROSITE:PS51312"
FT   REGION          170..229
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          243..269
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          315..349
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        197..229
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   440 AA;  48366 MW;  B641F65DE0DF76DB CRC64;
     MSPQNHEQVV TQAVMNRYVN VEKTKRDVLT ALQHYRGLGP KLDKFVFRSG TSRYLLCLEG
     TIPVTYKGST YNIPICIWLL DNHPLSSPMV YVKPTPDMLI KASRHVDQNG KVYLPYLHEW
     NPNSSDLPGL IQIMIMTFSE MPPVYSKPKT AQPPGATPYP LPYPTNSPGY MPMPGGGPNM
     PYSPAQTGAN TVYPPYPTQP GGYPPSTTPY PVYPPASTAG YPPSQPPTSY PPPYSAGGIT
     YPPYPSTTSS VPTGATETSG VTGTSTTTST GTITEEHIRA SLISAVSDRV RAKLRDSYGG
     SQAEVSVLRQ QQADLNQGKI KLEGLISKLE QEQTELDKNI RVLREKEGEI KNVLSRLSSA
     TEPLNVDEAV TTTAPLYKQL LNAYAEDQAT QDAIYYLGEA LRRDVIDLDC FLKHVRSLSR
     KQYQLRATMI KCRAKGNMAG
//