ID A0A3R7QNB8_PENVA Unreviewed; 408 AA.
AC A0A3R7QNB8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 22-FEB-2023, entry version 14.
DE SubName: Full=Suppressor of cytokine signaling 5 {ECO:0000313|EMBL:ROT84547.1};
GN ORFNames=C7M84_022259 {ECO:0000313|EMBL:ROT84547.1};
OS Penaeus vannamei (Whiteleg shrimp) (Litopenaeus vannamei).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC Malacostraca; Eumalacostraca; Eucarida; Decapoda; Dendrobranchiata;
OC Penaeoidea; Penaeidae; Penaeus.
OX NCBI_TaxID=6689 {ECO:0000313|EMBL:ROT84547.1, ECO:0000313|Proteomes:UP000283509};
RN [1] {ECO:0000313|EMBL:ROT84547.1, ECO:0000313|Proteomes:UP000283509}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Muscle {ECO:0000313|EMBL:ROT84547.1};
RA Zhang X., Yuan J., Li F., Xiang J.;
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ROT84547.1, ECO:0000313|Proteomes:UP000283509}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Muscle {ECO:0000313|EMBL:ROT84547.1};
RA Sun Y., Gao Y., Yu Y.;
RT "The decoding of complex shrimp genome reveals the adaptation for benthos
RT swimmer, frequently molting mechanism and breeding impact on genome.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ROT84547.1}.
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DR EMBL; QCYY01000529; ROT84547.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3R7QNB8; -.
DR STRING; 6689.A0A3R7QNB8; -.
DR Proteomes; UP000283509; Unassembled WGS sequence.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR10155; PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR10155:SF0; SUPPRESSOR OF CYTOKINE SIGNALING AT 36E, ISOFORM D; 1.
DR Pfam; PF00017; SH2; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR SMART; SM00252; SH2; 1.
DR SMART; SM00253; SOCS; 1.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50001; SH2; 1.
DR PROSITE; PS50225; SOCS; 1.
PE 4: Predicted;
KW Growth regulation {ECO:0000256|ARBA:ARBA00022604};
KW Reference proteome {ECO:0000313|Proteomes:UP000283509};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191};
KW Signal transduction inhibitor {ECO:0000256|ARBA:ARBA00022700};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 259..354
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT DOMAIN 349..398
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
FT REGION 1..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..32
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 408 AA; 45754 MW; F2E792F099E2C8BA CRC64;
MGQGSSYPHP VPPPQRPASP WAAEPPPEPA RSPHQQRQQL QRRQRHLRRG AAGTRPVGGG
GAGGEACVGA SGGACGSGGC GHWCSSCRVR VQVEVECVGA DARPSPPRAG RLRTLTFPKR
HRHKTKTPTR DLPAQPKKKK APWTFRLNCR LRTSKSEPEP EAAASPGAAV GCGACMCPSL
RRAEPEAHLR HHHHLAHHHH LPHHLHGRLP AAQEQPSTLL QQVGRLAGDG SLLQRTVHTQ
VDYIHCLVPD LLSITNCAFY WGKMDRYEAE RLLENRPEGT FLLRDSAQEE YLFSVSFRRY
GRSLHARIEQ WNHKFSFDSH DPGVFASDTV CGLIEHYKDP SCCMFFEPML TNPLARTFPF
PLQHLCRAAI CSATTYDGIN NIRLPKPLKN YLKEYHYKQR VRVRRLDH
//
