ID   A0A3R7QWI7_PENVA        Unreviewed;       147 AA.
AC   A0A3R7QWI7;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 10.
DE   RecName: Full=Adenosine 5'-monophosphoramidase HINT3 {ECO:0000256|ARBA:ARBA00039802};
DE   AltName: Full=Histidine triad nucleotide-binding protein 3 {ECO:0000256|ARBA:ARBA00042361};
GN   ORFNames=C7M84_000452 {ECO:0000313|EMBL:ROT80801.1};
OS   Penaeus vannamei (Whiteleg shrimp) (Litopenaeus vannamei).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC   Malacostraca; Eumalacostraca; Eucarida; Decapoda; Dendrobranchiata;
OC   Penaeoidea; Penaeidae; Penaeus.
OX   NCBI_TaxID=6689 {ECO:0000313|EMBL:ROT80801.1, ECO:0000313|Proteomes:UP000283509};
RN   [1] {ECO:0000313|EMBL:ROT80801.1, ECO:0000313|Proteomes:UP000283509}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Muscle {ECO:0000313|EMBL:ROT80801.1};
RA   Zhang X., Yuan J., Li F., Xiang J.;
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ROT80801.1, ECO:0000313|Proteomes:UP000283509}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Muscle {ECO:0000313|EMBL:ROT80801.1};
RA   Sun Y., Gao Y., Yu Y.;
RT   "The decoding of complex shrimp genome reveals the adaptation for benthos
RT   swimmer, frequently molting mechanism and breeding impact on genome.";
RL   Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=adenosine 5'-phosphoramidate + H2O = AMP + NH4(+);
CC         Xref=Rhea:RHEA:67916, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938,
CC         ChEBI:CHEBI:57890, ChEBI:CHEBI:456215;
CC         Evidence={ECO:0000256|ARBA:ARBA00024472};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ROT80801.1}.
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DR   EMBL; QCYY01001067; ROT80801.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3R7QWI7; -.
DR   STRING; 6689.A0A3R7QWI7; -.
DR   EnsemblMetazoa; XM_027355495.1; XP_027211296.1; LOC113804596.
DR   Proteomes; UP000283509; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.428.10; HIT-like; 1.
DR   InterPro; IPR001310; Histidine_triad_HIT.
DR   InterPro; IPR011146; HIT-like.
DR   InterPro; IPR036265; HIT-like_sf.
DR   PANTHER; PTHR12486:SF5; ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT3; 1.
DR   PANTHER; PTHR12486; APRATAXIN-RELATED; 1.
DR   Pfam; PF11969; DcpS_C; 1.
DR   PRINTS; PR00332; HISTRIAD.
DR   SUPFAM; SSF54197; HIT-like; 1.
DR   PROSITE; PS51084; HIT_2; 1.
PE   4: Predicted;
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000283509}.
FT   DOMAIN          15..123
FT                   /note="HIT"
FT                   /evidence="ECO:0000259|PROSITE:PS51084"
FT   MOTIF           106..110
FT                   /note="Histidine triad motif"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR601310-3,
FT                   ECO:0000256|PROSITE-ProRule:PRU00464"
FT   ACT_SITE        108
FT                   /note="Tele-AMP-histidine intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR601310-1"
SQ   SEQUENCE   147 AA;  16793 MW;  D2417E1534FB16ED CRC64;
     MSAPAQQQTD RGKCVFCRIC DGVEPNNILH QDDEFVVFPD IRPAAPHHYL IVPRHHYIDV
     KNLSADHIPM VEKMVSLSKE VLIAQGGCES TARLGFHWPP FHTVSHLHLH IIAPEAEMGF
     IARGMFKKDS FWFVSPETAI QRLRQKM
//