ID A0A3R7QXQ0_PENVA Unreviewed; 615 AA.
AC A0A3R7QXQ0;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE SubName: Full=Variant Ionotropic Glutamate Receptor {ECO:0000313|EMBL:ROT82236.1};
GN ORFNames=C7M84_024600 {ECO:0000313|EMBL:ROT82236.1};
OS Penaeus vannamei (Whiteleg shrimp) (Litopenaeus vannamei).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC Malacostraca; Eumalacostraca; Eucarida; Decapoda; Dendrobranchiata;
OC Penaeoidea; Penaeidae; Penaeus.
OX NCBI_TaxID=6689 {ECO:0000313|EMBL:ROT82236.1, ECO:0000313|Proteomes:UP000283509};
RN [1] {ECO:0000313|EMBL:ROT82236.1, ECO:0000313|Proteomes:UP000283509}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Muscle {ECO:0000313|EMBL:ROT82236.1};
RA Zhang X., Yuan J., Li F., Xiang J.;
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ROT82236.1, ECO:0000313|Proteomes:UP000283509}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Muscle {ECO:0000313|EMBL:ROT82236.1};
RA Sun Y., Gao Y., Yu Y.;
RT "The decoding of complex shrimp genome reveals the adaptation for benthos
RT swimmer, frequently molting mechanism and breeding impact on genome.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ROT82236.1}.
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DR EMBL; QCYY01000855; ROT82236.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3R7QXQ0; -.
DR Proteomes; UP000283509; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0050906; P:detection of stimulus involved in sensory perception; IEA:UniProt.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 1.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR PANTHER; PTHR42643; IONOTROPIC RECEPTOR 20A-RELATED; 1.
DR PANTHER; PTHR42643:SF13; IONOTROPIC RECEPTOR 20A-RELATED; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR SMART; SM00918; Lig_chan-Glu_bd; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:ROT82236.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000283509};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..615
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018660926"
FT TRANSMEM 328..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 397..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 582..601
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 220..280
FT /note="Ionotropic glutamate receptor L-glutamate and
FT glycine-binding"
FT /evidence="ECO:0000259|SMART:SM00918"
SQ SEQUENCE 615 AA; 70953 MW; 2668E79D554A5793 CRC64;
MLLSSLLWLS VLPFAPGTGA QNRDTPESHL VSLRGILEGP LAGWKAVFYL DPSLEAPVWE
YVRGLLVGRN ASYVLVDLGS DGALWSEEQP KELLRGNFMV HVVVFQNDPR PFFEAVSLQW
NPQYLLFFSA SNVTKNNLLL EDTFKGIERL LLVEKTYLTS SASRPVSGMF TSFPFEERKI
KSIGIWSNTK FASKEDLFVD RFESFRGYEF QLGTWFDDFP YLHQSKTKPE GYGDGVEVEM
LDAMARVLDF KYNFTTEPPD LKWGAFENGS WTGMLGMVHR EEKNFTVNYF VITGERVDAF
DASVSYWMEG FGMSMLSPPP LPKWRGTYYS FTPFVWLSLA VTFVLVLIII SIQDMLQPEP
FLGGVGSTWP YLLRAMFNNS IPRLPKAHWQ RLFVGSWWLY CFIVTTAYTA NLIAFLTIPV
FPGRIQTVQQ LAESDYRVSM FDYGEFVPGA LKSSRDPYYR ALGEKLDLYP TYDGSVHPML
EGTHAYIESY SYNRILIFVD YEADNSYMLR EQLYPGHLCW YFQKNTAWKY KFDHGIRRLV
ESGLIAHWIK VKTEDFLGRD FERRQQLQDK ERLNQALSLE HLQGVFFILA MSWAAGVLVF
AGEVLRHRCL LQELE
//
