ID A0A3R8M7L2_9CAUL Unreviewed; 586 AA.
AC A0A3R8M7L2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Chloride channel protein {ECO:0000313|EMBL:RRN63617.1};
GN ORFNames=EIK80_17345 {ECO:0000313|EMBL:RRN63617.1};
OS Caulobacter sp. 602-1.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Caulobacter.
OX NCBI_TaxID=2492472 {ECO:0000313|EMBL:RRN63617.1, ECO:0000313|Proteomes:UP000268773};
RN [1] {ECO:0000313|EMBL:RRN63617.1, ECO:0000313|Proteomes:UP000268773}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=602-1 {ECO:0000313|EMBL:RRN63617.1,
RC ECO:0000313|Proteomes:UP000268773};
RA Gao J., Sun J.;
RT "The genome of Caulobacter sp 602-1.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RRN63617.1}.
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DR EMBL; RRYI01000005; RRN63617.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3R8M7L2; -.
DR OrthoDB; 9814803at2; -.
DR Proteomes; UP000268773; Unassembled WGS sequence.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd02205; CBS_pair_SF; 1.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 26..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 319..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 344..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 521..577
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 586 AA; 61287 MW; 8752254F95ABA427 CRC64;
MPLSLPAPST ARWLAWLRRR TRSSELWLIA VAVLIGVAAG ALAVLQAKLA HGLQGLLFGI
NLGERLSAQS AIAPWRVLSI PLGGLLLGLL TWAWMTYRPR PAVDPVEANA LHGGRLSLKD
SAFICVQTLI SNGFGASVGL EAAYAQAGAA VASFAGQKLN LRRADMRTLV GAGAGAAIAA
AFGAPLTGAF YAFEIVIGAY TVANLAPVAA AALAAALVAS RMGAIPYLLK TTTPAVQSWL
DYGLYALLGL VCAAAGIGLM RLVALAERGV VRIGLPRGWR PAAGGLALAG LAMITPQILS
SGHGALHLDL ISDLGLKTLL MLVALKALAS VLSLSFGFRG GLFFASLFLG ALIGQTVSAL
SVAAPWLPGL DPTVAALVGM AALAVAVVGG PFTMSFLVLE ATGDFTVTAA ALVASLIAST
IVRETFGYSF STWRLHLRGE TIRSAHDVSW LRPLTAGRMM RKDVQTTAST TTLAEFRRRF
PLGSTRRVVM IDEAEHYAGV IVTALAYADP GGDERPVSVL AVNPDAALTP DQSIKEVMRA
FDSTEADELA VVDAERRVIG LVSEAHATRR YAEELEKVRR DLTGEA
//
