ID A0A3R9FPD0_9VIBR Unreviewed; 376 AA.
AC A0A3R9FPD0;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN ORFNames=EJA03_10355 {ECO:0000313|EMBL:RSD31129.1};
OS Vibrio pectenicida.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=62763 {ECO:0000313|EMBL:RSD31129.1, ECO:0000313|Proteomes:UP000269041};
RN [1] {ECO:0000313|EMBL:RSD31129.1, ECO:0000313|Proteomes:UP000269041}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CAIM 594 {ECO:0000313|EMBL:RSD31129.1,
RC ECO:0000313|Proteomes:UP000269041};
RA Gomez-Gil B., Enciso-Ibarra K.;
RT "Genomic taxonomy of the Vibrionaceae family.";
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RSD31129.1}.
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DR EMBL; RSFA01000041; RSD31129.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3R9FPD0; -.
DR OrthoDB; 9790967at2; -.
DR Proteomes; UP000269041; Unassembled WGS sequence.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Isomerase {ECO:0000313|EMBL:RSD31129.1}.
FT DOMAIN 19..359
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
SQ SEQUENCE 376 AA; 41893 MW; 5F0C506E8CEA1FD4 CRC64;
MTASVRFETL DCLEENTKVG MATLDNAPSL NALNYDMLVQ LKAQLEVWHE DDNIICVVIE
GQGDKAFCAG GDVRTMHDKM RDGSCEEIAG YCTSFFKLEY ECDYLIHTYC KPIIAWGHGI
VMGGGMGLFM GASHKVVTPQ SRLAMPEISI GLYPDVGGTW FLNKLDPGIG LFLGLTGVMV
NASDALGIRL ADHMVRAEDK EALLSRLKRT CWSEIEDVYR EVTRSLADIG NEVNGHQPDP
QMLPFINEIQ AACSGESVIQ VSENILNLSG QTKWMETAKN NHAQGSPITA HVCFEQLTRH
NDLSLADCFR LELNLSVRCC LLGEFREGVR ARLIDKDNQP KWIYNQVANV DETTIDTLFT
SLWSEQEHPL AQLGHY
//
