ID   A0A3R9RDG1_9BACI        Unreviewed;       362 AA.
AC   A0A3R9RDG1;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   03-MAY-2023, entry version 11.
DE   SubName: Full=M42 family peptidase {ECO:0000313|EMBL:RSL32990.1};
GN   ORFNames=D7Z54_13280 {ECO:0000313|EMBL:RSL32990.1};
OS   Salibacterium salarium.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae.
OX   NCBI_TaxID=284579 {ECO:0000313|EMBL:RSL32990.1, ECO:0000313|Proteomes:UP000275076};
RN   [1] {ECO:0000313|EMBL:RSL32990.1, ECO:0000313|Proteomes:UP000275076}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IM0101 {ECO:0000313|EMBL:RSL32990.1,
RC   ECO:0000313|Proteomes:UP000275076};
RA   Yamprayoonswat W., Boonvisut S., Jumpathong W., Sittihan S., Ruangsuj P.,
RA   Wanthongcharoen S., Thongpramul N., Pimmason S., Yu B., Yasawong M.;
RT   "Draft genome sequence of Bacillus salarius IM0101, isolated from a
RT   hypersaline soil in Inner Mongolia, China.";
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
CC         Evidence={ECO:0000256|PIRSR:PIRSR001123-2};
CC       Note=Binds 2 divalent metal cations per subunit.
CC       {ECO:0000256|PIRSR:PIRSR001123-2};
CC   -!- SIMILARITY: Belongs to the peptidase M42 family.
CC       {ECO:0000256|ARBA:ARBA00006272, ECO:0000256|PIRNR:PIRNR001123}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RSL32990.1}.
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DR   EMBL; RBVX01000011; RSL32990.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3R9RDG1; -.
DR   OrthoDB; 9772053at2; -.
DR   Proteomes; UP000275076; Unassembled WGS sequence.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd05656; M42_Frv; 1.
DR   Gene3D; 2.40.30.40; Peptidase M42, domain 2; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR008007; Peptidase_M42.
DR   InterPro; IPR023367; Peptidase_M42_dom2.
DR   PANTHER; PTHR32481; AMINOPEPTIDASE; 1.
DR   PANTHER; PTHR32481:SF21; AMINOPEPTIDASE YSDC-RELATED; 1.
DR   Pfam; PF05343; Peptidase_M42; 1.
DR   PIRSF; PIRSF001123; PepA_GA; 1.
DR   SUPFAM; SSF101821; Aminopeptidase/glucanase lid domain; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   3: Inferred from homology;
KW   Aminopeptidase {ECO:0000256|ARBA:ARBA00022438};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|PIRSR:PIRSR001123-2}; Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000275076}.
FT   ACT_SITE        214
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001123-1"
FT   BINDING         68
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001123-2"
FT   BINDING         182
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001123-2"
FT   BINDING         182
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001123-2"
FT   BINDING         215
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001123-2"
FT   BINDING         237
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001123-2"
FT   BINDING         325
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001123-2"
SQ   SEQUENCE   362 AA;  39238 MW;  CCF19D815BBD2B4F CRC64;
     MSNLDQTTNM LKELTDANGI PGNEKEARDV MRDNISPYAD DITTDHLGSL IAKKTGKAGG
     PKIMITGHLD EIGFMITQID DNGFLKFQTV GGWWSQVMLA QRVNIMTKKG NIVGVIGSKP
     PHILTAEQRK KAVEIKDMFI DIGASSKEEA ESFGVVPGDS VVPICDFTVM NNEKLMMAKA
     WDNRIGCAIA IEVMKRLQNE DHANEVYGVG AVQEEVGLRG AKTSANKITP DIGFAVDVGI
     AGDTPGVTEN DAKAEIGKGP QILVFDRSMV SHKGLRDFVT ETADKHDIPY QFDAMSGGAT
     DGGSIHLSGE GVPSLAITIP TRYIHTHAAI LHYDDFEHAV QLFVEIVKGL DEEKVKSITF
     DV
//