ID A0A3R9SJW7_9ACTN Unreviewed; 318 AA.
AC A0A3R9SJW7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=DeoR/GlpR transcriptional regulator {ECO:0000313|EMBL:RSR95703.1};
GN ORFNames=EF917_24930 {ECO:0000313|EMBL:RSR95703.1};
OS Streptomyces sp. WAC00469.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2487415 {ECO:0000313|EMBL:RSR95703.1, ECO:0000313|Proteomes:UP000269080};
RN [1] {ECO:0000313|EMBL:RSR95703.1, ECO:0000313|Proteomes:UP000269080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WAC00469 {ECO:0000313|EMBL:RSR95703.1,
RC ECO:0000313|Proteomes:UP000269080};
RA Culp E., Yim G., Waglechner N., Wang W., Pawlowski A.C., Wright G.D.;
RT "Unmasking the antibiotic production potential of Actinomycetes through
RT CRISPR/Cas9 inactivation of ubiquitous gene clusters.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RSR95703.1}.
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DR EMBL; RPRX01000123; RSR95703.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3R9SJW7; -.
DR OrthoDB; 7688673at2; -.
DR Proteomes; UP000269080; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR014036; DeoR_C.
DR InterPro; IPR001034; DeoR_HTH.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR018356; Tscrpt_reg_HTH_DeoR_CS.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30363:SF4; GLYCEROL-3-PHOSPHATE REGULON REPRESSOR; 1.
DR PANTHER; PTHR30363; HTH-TYPE TRANSCRIPTIONAL REGULATOR SRLR-RELATED; 1.
DR Pfam; PF00455; DeoRC; 1.
DR Pfam; PF08220; HTH_DeoR; 1.
DR PRINTS; PR00037; HTHLACR.
DR SMART; SM01134; DeoRC; 1.
DR SMART; SM00420; HTH_DEOR; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00894; HTH_DEOR_1; 1.
DR PROSITE; PS51000; HTH_DEOR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000269080};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 3..58
FT /note="HTH deoR-type"
FT /evidence="ECO:0000259|PROSITE:PS51000"
FT REGION 256..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 268..282
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 318 AA; 33487 MW; 95F4D075C5B2B27B CRC64;
MFAAERRQLI LEMVRANGAV SLRELARVVQ TSEVTVRRDV RALEAEGLLD RRHGGAVLPG
GFTRESGFPQ KSHLATAEKT VIADLAAGLV DEGEAIVVGA GTTTQELARR LARVPGLTVV
TNSLLVAQAL AHANRVEVVM TGGTLRGSNY ALVGSGAEQS LHGLRVSKAF LSGSGLTAER
GLSTSNMLSA SVDRALVQAA AEVVVLADHT KLGADTMFQT VPTELITRLV TNDPPAHDER
AATELQALAD QGVQISVAGP TGKPVHEQQP ARSERRRDVA LPGPRRGQVA GPSALRSAPL
GAEQPSERAA RVADLRRR
//
