ID A0A3R9U9S2_9ACTN Unreviewed; 575 AA.
AC A0A3R9U9S2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=DNA repair protein RecN {ECO:0000256|ARBA:ARBA00021315, ECO:0000256|PIRNR:PIRNR003128};
DE AltName: Full=Recombination protein N {ECO:0000256|ARBA:ARBA00033408, ECO:0000256|PIRNR:PIRNR003128};
GN Name=recN {ECO:0000313|EMBL:RSS02363.1};
GN ORFNames=EF917_14910 {ECO:0000313|EMBL:RSS02363.1};
OS Streptomyces sp. WAC00469.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2487415 {ECO:0000313|EMBL:RSS02363.1, ECO:0000313|Proteomes:UP000269080};
RN [1] {ECO:0000313|EMBL:RSS02363.1, ECO:0000313|Proteomes:UP000269080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WAC00469 {ECO:0000313|EMBL:RSS02363.1,
RC ECO:0000313|Proteomes:UP000269080};
RA Culp E., Yim G., Waglechner N., Wang W., Pawlowski A.C., Wright G.D.;
RT "Unmasking the antibiotic production potential of Actinomycetes through
RT CRISPR/Cas9 inactivation of ubiquitous gene clusters.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in recombinational repair of damaged DNA.
CC {ECO:0000256|ARBA:ARBA00003618, ECO:0000256|PIRNR:PIRNR003128}.
CC -!- SIMILARITY: Belongs to the RecN family. {ECO:0000256|ARBA:ARBA00009441,
CC ECO:0000256|PIRNR:PIRNR003128}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RSS02363.1}.
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DR EMBL; RPRX01000043; RSS02363.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3R9U9S2; -.
DR OrthoDB; 9806954at2; -.
DR Proteomes; UP000269080; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd03241; ABC_RecN; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR004604; DNA_recomb/repair_RecN.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR NCBIfam; TIGR00634; recN; 1.
DR PANTHER; PTHR11059; DNA REPAIR PROTEIN RECN; 1.
DR PANTHER; PTHR11059:SF0; DNA REPAIR PROTEIN RECN; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF003128; RecN; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|PIRNR:PIRNR003128};
KW DNA repair {ECO:0000256|PIRNR:PIRNR003128};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000269080}.
FT DOMAIN 12..528
FT /note="RecF/RecN/SMC N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02463"
FT COILED 342..376
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 575 AA; 60182 MW; 009DB3B4F8AE1537 CRC64;
MRIRSLGVID DAVVELSPGF TAVTGETGAG KTMVVTSLGL LLGGRADPAL VRIGAGKAVV
EGRVTVPADG PVALRAEEAG AELDDGALLI SRTVSAEGRS RAHVGGRSVP VGLLAELAED
LVAVHGQSDQ QGLLKPSRQR QALDRYAGDA VAVPLAKYSE AYRRLRAVTA ELEEITTRAR
ERAQEAGMLR YGLDEIAAVE PRPGEDAQLA EEAERLGHAE ALSSAATAAH AALAGDPEDP
EGIDAATLVA GAQRALQAVR SHDPALAALS DRLGEIGILL GDVAGELAGY AGDLDADPLR
LAAVEERRAA LGGLMRKYGE FDRGIDAVLE WAERSAARLA ELDNDDDRIE ELTAERDALR
AELGELAQAL TDARTQAAER FAEAVTAELA SLAMPHARVS FAVRQTEDPD GVEVGGRRVA
YGPFGVDEVE LLLAPHPGAP PRPIAKGASG GELSRVMLAV EVVFAGTDPV PTYLFDEVDA
GVGGKAAVEI GRRLAKLAKT AQVVVVTHLP QVAAFADRQL LVEKTDDGSV TRSGVKVLEG
EDRIRELSRM LAGQEDSATA RAHAEELLAT ARAEV
//
