ID   A0A3R9WBL7_9ACTN        Unreviewed;       337 AA.
AC   A0A3R9WBL7;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   08-NOV-2023, entry version 11.
DE   SubName: Full=PHP domain-containing protein {ECO:0000313|EMBL:RSS79833.1};
GN   ORFNames=EF918_15810 {ECO:0000313|EMBL:RSS79833.1};
OS   Streptomyces sp. WAC06614.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2487416 {ECO:0000313|EMBL:RSS79833.1, ECO:0000313|Proteomes:UP000277644};
RN   [1] {ECO:0000313|EMBL:RSS79833.1, ECO:0000313|Proteomes:UP000277644}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WAC06614 {ECO:0000313|EMBL:RSS79833.1,
RC   ECO:0000313|Proteomes:UP000277644};
RA   Culp E., Yim G., Waglechner N., Wang W., Pawlowski A.C., Wright G.D.;
RT   "Unmasking the antibiotic production potential of Actinomycetes through
RT   CRISPR/Cas9 inactivate of ubiquitous gene clusters.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RSS79833.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; RPRY01000099; RSS79833.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3R9WBL7; -.
DR   OrthoDB; 9808747at2; -.
DR   Proteomes; UP000277644; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd07436; PHP_PolX; 1.
DR   Gene3D; 1.10.150.110; DNA polymerase beta, N-terminal domain-like; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR010996; DNA_pol_b-like_N.
DR   InterPro; IPR027421; DNA_pol_lamdba_lyase_dom_sf.
DR   InterPro; IPR004013; PHP_dom.
DR   InterPro; IPR003141; Pol/His_phosphatase_N.
DR   InterPro; IPR016195; Pol/histidinol_Pase-like.
DR   InterPro; IPR047967; PolX_PHP.
DR   InterPro; IPR017078; UCP036978_PHPhdr.
DR   PANTHER; PTHR36928; PHOSPHATASE YCDX-RELATED; 1.
DR   PANTHER; PTHR36928:SF1; PHOSPHATASE YCDX-RELATED; 1.
DR   Pfam; PF14716; HHH_8; 1.
DR   Pfam; PF02811; PHP; 1.
DR   PIRSF; PIRSF036978; UCP036978_PHPhdr; 1.
DR   SMART; SM00481; POLIIIAc; 1.
DR   SUPFAM; SSF47802; DNA polymerase beta, N-terminal domain-like; 1.
DR   SUPFAM; SSF89550; PHP domain-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000277644}.
FT   DOMAIN          103..182
FT                   /note="Polymerase/histidinol phosphatase N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00481"
SQ   SEQUENCE   337 AA;  36696 MW;  F48F63656ED93159 CRC64;
     MDPVAALRRI AFLLERAQAP TYRVRAFRTA AERVAALPEG EAARRAAAGT LQAVKGIGPT
     TAEVIAEALA GRVPAYLERL EEELGAPSVP EGRGSALRAA LRGDCHLHSD WSDGGSTIED
     MGRTAAELGH EWAVLTDHSP RLTVARGLPP DRLREQLEVV AELNATWAPF RLLTGIECDI
     LDDGSLDQEP ELLERLDLVV VSVHSKLRMD RRAMTRRMVA AVRNPHADVL GHCTGRLLTG
     RTRPESEFDA AEVFAACAES GTAVEINSRP ERLDPPRRLL REAVAAGTYF AIDTDAHAPG
     QLSWQIAGCA RAEECGVPAE RVVNTWPVDR LLAWTHR
//