ID   A0A3R9WMQ3_9ACTN        Unreviewed;       257 AA.
AC   A0A3R9WMQ3;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=SDR family NAD(P)-dependent oxidoreductase {ECO:0000313|EMBL:RSS79058.1};
GN   ORFNames=EF918_18720 {ECO:0000313|EMBL:RSS79058.1};
OS   Streptomyces sp. WAC06614.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2487416 {ECO:0000313|EMBL:RSS79058.1, ECO:0000313|Proteomes:UP000277644};
RN   [1] {ECO:0000313|EMBL:RSS79058.1, ECO:0000313|Proteomes:UP000277644}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WAC06614 {ECO:0000313|EMBL:RSS79058.1,
RC   ECO:0000313|Proteomes:UP000277644};
RA   Culp E., Yim G., Waglechner N., Wang W., Pawlowski A.C., Wright G.D.;
RT   "Unmasking the antibiotic production potential of Actinomycetes through
RT   CRISPR/Cas9 inactivate of ubiquitous gene clusters.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000256|ARBA:ARBA00006484, ECO:0000256|RuleBase:RU000363}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RSS79058.1}.
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DR   EMBL; RPRY01000128; RSS79058.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3R9WMQ3; -.
DR   OrthoDB; 9810734at2; -.
DR   Proteomes; UP000277644; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd05233; SDR_c; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   PANTHER; PTHR44196; DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B; 1.
DR   PANTHER; PTHR44196:SF5; POSSIBLE MULTI-FUNCTIONAL ENZYME WITH ACYL-COA-REDUCTASE ACTIVITY ACRA1; 1.
DR   Pfam; PF00106; adh_short; 1.
DR   PIRSF; PIRSF000126; 11-beta-HSD1; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SMART; SM00822; PKS_KR; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000277644}.
SQ   SEQUENCE   257 AA;  27757 MW;  D839C570A2AFAC6F CRC64;
     MTTALITGST AGIGAAFARR LAAQKHNLVL VARDTKRLRE QATELHDRHG IEAEVLTADL
     STEEGIAAVE RRLSDRTHPV DLLVNNAGFG NKGRYLEVPM ADELTMLKVH IEAVLRLTSA
     ATESMRSRGR GAVVNVASVA AFVPRGTYGA SKAWVVQFTQ GAARDLADSG VRLMALCPGF
     VRTEFHQRAG MGTDNIPNWM WLDADKLVTE ALADLARGRT VSIPDPRYKA LMGLVKLTPR
     GLLGGVSSRT GRKYGPQ
//