ID A0A3S0AAY9_9ACTN Unreviewed; 578 AA.
AC A0A3S0AAY9;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=GGDEF and EAL domain-containing protein {ECO:0000313|EMBL:RSS00782.1};
GN ORFNames=EF917_16760 {ECO:0000313|EMBL:RSS00782.1};
OS Streptomyces sp. WAC00469.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2487415 {ECO:0000313|EMBL:RSS00782.1, ECO:0000313|Proteomes:UP000269080};
RN [1] {ECO:0000313|EMBL:RSS00782.1, ECO:0000313|Proteomes:UP000269080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WAC00469 {ECO:0000313|EMBL:RSS00782.1,
RC ECO:0000313|Proteomes:UP000269080};
RA Culp E., Yim G., Waglechner N., Wang W., Pawlowski A.C., Wright G.D.;
RT "Unmasking the antibiotic production potential of Actinomycetes through
RT CRISPR/Cas9 inactivation of ubiquitous gene clusters.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RSS00782.1}.
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DR EMBL; RPRX01000051; RSS00782.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3S0AAY9; -.
DR OrthoDB; 23692at2; -.
DR Proteomes; UP000269080; Unassembled WGS sequence.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000269080}.
FT DOMAIN 161..301
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 310..574
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
FT REGION 77..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 578 AA; 62318 MW; 0A7065652F81B3FF CRC64;
MVVSANDTFG ALLGTPAGDL TGRPATELVD LTSDGRTRRA YGEVLRGRQS RLRCTRRLKH
ADGRSLWVQV TLAPLPPERP AAHRRRAQPH GTGTASPDGG ARRFPGVLLS VADVSARREL
QARLRHARLH DPVTRLPNRT MFLERLAQAL EAESAASGTS GRIGLCHLDL DGFKAVNDTL
GHRTGDRLLA AVARRLTGCA DRAACGRGGA PLVARLGGDE FALLVEGSTG TEQLADLAES
VLTALQEPFE IDGRKLSVSA SIGVVERQAA GTTATALMQA ADTTLYWAKA DGRARWTLFD
PERNAHLMAR QALVSTLRPA VERGEFTLEY QPLVGLADGR LRGVEALVRW RHPQFGVLAP
NRFIALAEED GSIVPLGRWV LATACRQARD WQLAHPDEPP IFVSVNVAVR QVWDSDLVAD
VAEVLTRTQL PPGLLQLELT ESAVMGSAGR PLEALRALSD MGVRIAIDDF GTGYSNLAYL
SRLPVSALKL DGSFVRGFQR LAGAAQPPSP ADEVIVEAMI QLAHRLGLTV TAECVETDDQ
ASRLRRIGCD TGQGWLYSRP VSPDRISELL GGHACGRR
//
