ID   A0A3S0CN54_9ACTN        Unreviewed;       249 AA.
AC   A0A3S0CN54;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 12.
DE   SubName: Full=NUDIX domain-containing protein {ECO:0000313|EMBL:RSS78460.1};
GN   ORFNames=EF918_20910 {ECO:0000313|EMBL:RSS78460.1};
OS   Streptomyces sp. WAC06614.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2487416 {ECO:0000313|EMBL:RSS78460.1, ECO:0000313|Proteomes:UP000277644};
RN   [1] {ECO:0000313|EMBL:RSS78460.1, ECO:0000313|Proteomes:UP000277644}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WAC06614 {ECO:0000313|EMBL:RSS78460.1,
RC   ECO:0000313|Proteomes:UP000277644};
RA   Culp E., Yim G., Waglechner N., Wang W., Pawlowski A.C., Wright G.D.;
RT   "Unmasking the antibiotic production potential of Actinomycetes through
RT   CRISPR/Cas9 inactivate of ubiquitous gene clusters.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the Nudix hydrolase family.
CC       {ECO:0000256|ARBA:ARBA00005582}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RSS78460.1}.
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DR   EMBL; RPRY01000155; RSS78460.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3S0CN54; -.
DR   OrthoDB; 9786141at2; -.
DR   Proteomes; UP000277644; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR   InterPro; IPR020084; NUDIX_hydrolase_CS.
DR   InterPro; IPR000086; NUDIX_hydrolase_dom.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR43736; ADP-RIBOSE PYROPHOSPHATASE; 1.
DR   PANTHER; PTHR43736:SF4; DIHYDRONEOPTERIN TRIPHOSPHATE DIPHOSPHATASE; 1.
DR   Pfam; PF00293; NUDIX; 1.
DR   SUPFAM; SSF55811; Nudix; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51462; NUDIX; 1.
DR   PROSITE; PS00893; NUDIX_BOX; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000277644}.
FT   DOMAIN          11..154
FT                   /note="Nudix hydrolase"
FT                   /evidence="ECO:0000259|PROSITE:PS51462"
SQ   SEQUENCE   249 AA;  26395 MW;  ED790F9B13CD6E66 CRC64;
     MSPYDPSAFP PFAVTVDLVV LTVRRHALCA LVVKRGEPPF QGRWALPGGF VRGDEDLAAA
     AARELAEETG LCAHDPGRPG VDNGAHLEQL ATYGDPRRDP RMRVVSVAHL VLAPDLPAPR
     AGGDANSARW APVDELLAAG DADAPGGLAF DHAQILADGV ERARSKIEYS SLATAFCPAE
     FTVGELRRVY EAVWGVALDP RNFHRKVTGT PGFLVPAGGT TTRQGGRPAQ LFRAGGATLL
     NPPMLRPEV
//