ID   A0A3S0HMN7_9BACI        Unreviewed;       363 AA.
AC   A0A3S0HMN7;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   13-SEP-2023, entry version 12.
DE   SubName: Full=NAD(P)-dependent alcohol dehydrogenase {ECO:0000313|EMBL:RTQ94467.1};
GN   ORFNames=EKG35_05470 {ECO:0000313|EMBL:RTQ94467.1};
OS   Lysinibacillus telephonicus.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Lysinibacillus.
OX   NCBI_TaxID=1714840 {ECO:0000313|EMBL:RTQ94467.1, ECO:0000313|Proteomes:UP000276349};
RN   [1] {ECO:0000313|EMBL:RTQ94467.1, ECO:0000313|Proteomes:UP000276349}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S5H2222 {ECO:0000313|EMBL:RTQ94467.1,
RC   ECO:0000313|Proteomes:UP000276349};
RA   Yu L.;
RL   Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|RuleBase:RU361277};
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|ARBA:ARBA00008072, ECO:0000256|RuleBase:RU361277}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RTQ94467.1}.
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DR   EMBL; RXNR01000011; RTQ94467.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3S0HMN7; -.
DR   OrthoDB; 9806940at2; -.
DR   Proteomes; UP000276349; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd08278; benzyl_alcohol_DH; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR43880; ALCOHOL DEHYDROGENASE; 1.
DR   PANTHER; PTHR43880:SF12; ALCOHOL DEHYDROGENASE CLASS-3; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|RuleBase:RU361277};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000276349};
KW   Zinc {ECO:0000256|RuleBase:RU361277}.
FT   DOMAIN          12..359
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   363 AA;  38534 MW;  605EEFDBFE9A4789 CRC64;
     MKIKAAITHA QGEPFKIEEV ELADPKSNEV LVKIVASGVC HTDAVARDAA IAPLPAVLGH
     EGSGIVERVG EGVTTIQPGD HVVLSFAHCG HCENCLTGHP TVCETFNDLN FGGINDDHTH
     RLSQDGKDLS TFFGQSSFGT YAISHERNVV KVDKDVDLAL LGPLGCGIQT GAGTVLNRIQ
     PEFGSTIAIY GAGAVGLSAI MAAAIVGCKT IIAVDVHDSR LELAKKLGAT HTFNGSKVDV
     VKEIKAITNG GTHYAVDTTG VPPVVRQCLQ ALRPLGTAAI VGVTPEMTID VHNDLMAEGK
     TMMGVIEGDA VPRVFIPQLV EYYKAGKFPF DKLVKYFEFD QINEAFEASK NGSVIKPILK
     IQQ
//