ID A0A3S0W8W6_9BACI Unreviewed; 580 AA.
AC A0A3S0W8W6;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=DUF4080 domain-containing protein {ECO:0000313|EMBL:RUQ30236.1};
GN ORFNames=ELQ35_07815 {ECO:0000313|EMBL:RUQ30236.1};
OS Peribacillus cavernae.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Peribacillus.
OX NCBI_TaxID=1674310 {ECO:0000313|EMBL:RUQ30236.1, ECO:0000313|Proteomes:UP000267430};
RN [1] {ECO:0000313|EMBL:RUQ30236.1, ECO:0000313|Proteomes:UP000267430}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L5 {ECO:0000313|EMBL:RUQ30236.1,
RC ECO:0000313|Proteomes:UP000267430};
RA Seuylemezian A., Vaishampayan P.;
RT "Bacillus chawlae sp. nov., Bacillus glennii sp. nov., and Bacillus saganii
RT sp. nov. Isolated from the Vehicle Assembly Building at Kennedy Space
RT Center where the Viking Spacecraft were Assembled.";
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RUQ30236.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; RYZZ01000007; RUQ30236.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3S0W8W6; -.
DR OrthoDB; 9801424at2; -.
DR Proteomes; UP000267430; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd02068; radical_SAM_B12_BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR025288; DUF4080.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR PANTHER; PTHR43409:SF18; RADICAL SAM SUPERFAMILY PROTEIN; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF13311; DUF4080; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000267430}.
FT DOMAIN 1..133
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 172..403
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 580 AA; 67589 MW; 0F4A0160E03F3DCA CRC64;
MKTVIATLNA KYIHTSLSIR YLKAYAAPDF DVQLAEYTIK DPIMNIVGDL YSKKPDIIGF
SCYIWNIEET IKVIQMLRKI NQELVIILGG PEVTYDVTEW LKKVPEADFI VIGEGETTFK
KLLTQLHDRK DYSGISGIAY RKEGKNVIQP QGEKLNLKEL SSPFRFEEDI SQLSKRVTYI
ETSRGCPFNC QFCLSSIEVG VRYFDREKVK EDIRYLMENG ARTIKFVDRT FNISRSYAME
MFQFLIDEHV PGTVFQFEIT ADIMRPEVIQ FLNDHAPAGL FRFEIGVQST NDYTNELVMR
KQNFEKLTRT VTMVKEGGKI DQHLDLIAGL PEEDYPSFRK TFNEVFELRP EELQLGFLKM
LRGTGLRIRA KDHAYIFSDQ SPYEILGNNV LSFDDIVKIK QVEDVLEKYW NDHRMDRTVE
FLVTTAFSSP FDFFQDFGTY WDEQGWSRIG HQLEDLFRRL QQFLQEVNPA VLDIAVGLMK
YDYFHNQKYK PRKPWWNQTF DKAGRSGIYE SILEDPSTLG SDYESLHLTE KELFKHSMLE
ELPFNLKTFL ETGLIDPKST IMLTYFEPAG TGSQTFSYVK
//
