ID   A0A3S0WSE8_9GAMM        Unreviewed;      1272 AA.
AC   A0A3S0WSE8;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Zn-dependent protease with chaperone function {ECO:0000313|EMBL:RUL69084.1};
GN   ORFNames=EKH80_22945 {ECO:0000313|EMBL:RUL69084.1};
OS   Dyella choica.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC   Rhodanobacteraceae; Dyella.
OX   NCBI_TaxID=1927959 {ECO:0000313|EMBL:RUL69084.1, ECO:0000313|Proteomes:UP000274358};
RN   [1] {ECO:0000313|EMBL:RUL69084.1, ECO:0000313|Proteomes:UP000274358}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=4M-K27 {ECO:0000313|EMBL:RUL69084.1,
RC   ECO:0000313|Proteomes:UP000274358};
RA   Qiu L.-H., Gao Z.-H.;
RT   "Dyella dinghuensis sp. nov. DHOA06 and Dyella choica sp. nov. 4M-K27,
RT   isolated from forest soil.";
RL   Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RUL69084.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; RYYV01000039; RUL69084.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3S0WSE8; -.
DR   OrthoDB; 9789270at2; -.
DR   Proteomes; UP000274358; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd07328; M48_Ste24p_like; 1.
DR   Gene3D; 3.30.2010.10; Metalloproteases ('zincins'), catalytic domain; 1.
DR   InterPro; IPR001915; Peptidase_M48.
DR   PANTHER; PTHR43221; PROTEASE HTPX; 1.
DR   PANTHER; PTHR43221:SF1; PROTEASE HTPX; 1.
DR   Pfam; PF01435; Peptidase_M48; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:RUL69084.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000274358};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   TRANSMEM        27..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        65..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        221..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          107..369
FT                   /note="Peptidase M48"
FT                   /evidence="ECO:0000259|Pfam:PF01435"
SQ   SEQUENCE   1272 AA;  140129 MW;  6D7CC807CA13D485 CRC64;
     MNVIYPAGPA QVPEGFTRPS GTYMRHAWMA VGALLLFMAL YFALAAWFVY NGIAELGRAA
     GDGGFLAALV GVGSLFLAFF LIKALFFIKK GAQNDGIELT RADQPSLFAF LDRIADEAGA
     PRPHKVYASG RVNAAVSYDL SLLNLLFPSR KNLEIGLGLV NMLNLGEFKA VCAHEFGHFG
     QRSMAVGRWV YTAQQVAAHI VTRRDALDSF LRGLSRLDIR IAWIGWLLGI VIWALRVIVD
     AGFRLVVLAQ RALAREMELQ ADLVAVSLTG SDALVHALHR LRMADDAWDR SLNFLRGEVG
     AKRPPRDIFA VQEALADRLG LIYNDPGYAR RPQLPAEGGA AFRVFESELA QPPRMWSTHP
     MNHERESNAK RTYLFAPADE RSAWSIFEHE QGLRERMTHE LAGKPAEPTV ELDETLKRLD
     EQFAREHLKP DYRGIYLGMS AVRHASSPGE LYYENAVPRL PLSLEDLYPQ RIGEELDRLQ
     ALDREHALLC SLRDRVYDAP DGVIRHRGRI LKRSQLPAVI AEVEKEHTGV RASLHSTLRR
     VRSLHLKVAA TLAPAWRDYL LGSLHVLHYA DHAEANLRDA QAALAKDYRQ AAARGSINEN
     GVRRILAGAS DVHRAISRIF NEAATVKPGA RILARLGASS WPQALGNYGL RAPERANINE
     WLRHIDGWIN HTANWLSALR RTTLDELLAV EASIAAATRD AALGEAPADM PSAHDEYPTL
     VPGSERGQQI KQGFRQRFES VGDRISGVGK ASAALAIVGS VLAFGWLHES TDVTVYNPLD
     RAVVAKVDGH RVNLQPHQHA DISLRGEGQV EVDAQTDDGE PIEHFSAPVD RSDDKIIYTV
     AAAAPLHSWM ASYGSAPRTT ASLLSPQRWQ VVHADFVFTQ PPHSIQTNSG QGVRTVLDGL
     DAAPPEFYAD QVHDQRAVAQ MMLAHVRFDK PDSINLWSWL ELARSMPGFD QAFAERRKHF
     PFDVLAMRLE QDHAIGATYE EICARDQSLA QASPEQPDLA YAATRCLAPG PAQDRKFAEG
     AQRWPHSPWF AMASAFAEAQ QQHYPQALEL YTRATNQSLA LRNSIATEVV RLSRLVDPAG
     TMQRQSQLAA VSPALANLLL LEPGSAMQDD PQYRALSLLS DGRLDNALTT SAHTPMEGHV
     LRMVAASQGA SAVLRARAAA LPKGVGVDQE TVWLALAQGG DANDPAVAKV LERLEAGYGR
     EGHAWMESMQ RFVEFARRGD AANAERALTG VPMEMRAQAY VAGIYLLGPM APDAWRHFAR
     AILFAGERPF LG
//