ID A0A3S0XI10_9GAMM Unreviewed; 343 AA.
AC A0A3S0XI10;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase {ECO:0000313|EMBL:RUR13651.1};
DE EC=2.3.1.191 {ECO:0000313|EMBL:RUR13651.1};
GN Name=lpxD {ECO:0000313|EMBL:RUR13651.1};
GN ORFNames=ELY15_01670 {ECO:0000313|EMBL:RUR13651.1};
OS Legionella sp. km772.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=2498111 {ECO:0000313|EMBL:RUR13651.1, ECO:0000313|Proteomes:UP000287796};
RN [1] {ECO:0000313|EMBL:RUR13651.1, ECO:0000313|Proteomes:UP000287796}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=km772 {ECO:0000313|Proteomes:UP000287796};
RA Wu H.;
RT "Legionella sp,whole genome shotgun sequence.";
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RUR13651.1}.
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DR EMBL; RZGQ01000007; RUR13651.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3S0XI10; -.
DR OrthoDB; 9784739at2; -.
DR Proteomes; UP000287796; Unassembled WGS sequence.
DR GO; GO:0016410; F:N-acyltransferase activity; IEA:InterPro.
DR GO; GO:0103118; F:UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009245; P:lipid A biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd03352; LbH_LpxD; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR Gene3D; 3.40.1390.10; MurE/MurF, N-terminal domain; 1.
DR InterPro; IPR001451; Hexapep.
DR InterPro; IPR018357; Hexapep_transf_CS.
DR InterPro; IPR007691; LpxD.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR InterPro; IPR020573; UDP_GlcNAc_AcTrfase_non-rep.
DR NCBIfam; TIGR01853; lipid_A_lpxD; 1.
DR PANTHER; PTHR43378; UDP-3-O-ACYLGLUCOSAMINE N-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR43378:SF2; UDP-3-O-ACYLGLUCOSAMINE N-ACYLTRANSFERASE 1, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF00132; Hexapep; 3.
DR Pfam; PF04613; LpxD; 1.
DR SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
DR PROSITE; PS00101; HEXAPEP_TRANSFERASES; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000313|EMBL:RUR13651.1};
KW Lipid A biosynthesis {ECO:0000256|ARBA:ARBA00022556};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000287796};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:RUR13651.1}.
FT DOMAIN 27..91
FT /note="UDP-3-O-[3-hydroxymyristoyl] glucosamine N-
FT acyltransferase non-repeat region"
FT /evidence="ECO:0000259|Pfam:PF04613"
SQ SEQUENCE 343 AA; 36350 MW; D38D681F1FFEB04D CRC64;
MNDLSGFTLE QLARLVDGVA HGNAQYAISS LSSLTRAQAS HITYFDNPLL KDALRSTQAG
IIVLKEEHLA WCPSHAIIVS DPLAAIKQIA TLFTPSVKPA FIDPSATIHP SVQIGHNVSI
GPYAVVGENV QLADGVHLGA HSCIHNSVTI GKNSYLDCQV TVHSNTQIGA DVVVNAGVVL
GAAPYNYVKE HGHWQQGLSL GGLIIADKVH LGANTVIDRG AVGDTYLGQG VCIDNLVHIA
HDVYIGAHTA IAGCAVLGAH VIIGNDCIIG GASCLAANIS LTDDVVISGM STVNKSLTKS
GIYSSGTLIH EHQRWRKNAA RFRRLDDYIT KLTTLERKIN SEN
//
