ID A0A3S0Z4K2_ELYCH Unreviewed; 262 AA.
AC A0A3S0Z4K2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Spindle and kinetochore-associated protein 2 {ECO:0000256|ARBA:ARBA00017139};
DE AltName: Full=Protein FAM33A {ECO:0000256|ARBA:ARBA00029651};
DE Flags: Fragment;
GN ORFNames=EGW08_021678 {ECO:0000313|EMBL:RUS70564.1};
OS Elysia chlorotica (Eastern emerald elysia) (Sea slug).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Sacoglossa; Placobranchoidea;
OC Plakobranchidae; Elysia.
OX NCBI_TaxID=188477 {ECO:0000313|EMBL:RUS70564.1, ECO:0000313|Proteomes:UP000271974};
RN [1] {ECO:0000313|EMBL:RUS70564.1, ECO:0000313|Proteomes:UP000271974}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EC2010 {ECO:0000313|EMBL:RUS70564.1};
RC TISSUE=Whole organism of an adult {ECO:0000313|EMBL:RUS70564.1};
RA Cai H., Li Q., Fang X., Li J., Curtis N.E., Altenburger A., Shibata T.,
RA Feng M., Maeda T., Schwartz J.A., Shigenobu S., Lundholm N., Nishiyama T.,
RA Yang H., Hasebe M., Li S., Pierce S.K., Wang J.;
RT "A draft genome assembly of the solar-powered sea slug Elysia chlorotica.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Chromosome, centromere, kinetochore
CC {ECO:0000256|ARBA:ARBA00004629}. Cytoplasm, cytoskeleton, spindle
CC {ECO:0000256|ARBA:ARBA00004186}.
CC -!- SIMILARITY: Belongs to the SKA2 family.
CC {ECO:0000256|ARBA:ARBA00010684}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RUS70564.1}.
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DR EMBL; RQTK01001381; RUS70564.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3S0Z4K2; -.
DR STRING; 188477.A0A3S0Z4K2; -.
DR Proteomes; UP000271974; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0000940; C:outer kinetochore; IEA:InterPro.
DR GO; GO:0005876; C:spindle microtubule; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007059; P:chromosome segregation; IEA:InterPro.
DR Gene3D; 6.10.250.1380; -; 1.
DR InterPro; IPR026762; Ska2.
DR InterPro; IPR042091; Ska2_N.
DR PANTHER; PTHR32017; SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 2; 1.
DR PANTHER; PTHR32017:SF3; SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF11362; DUF3161; 1.
DR Pfam; PF16740; SKA2; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Centromere {ECO:0000256|ARBA:ARBA00023328};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Kinetochore {ECO:0000256|ARBA:ARBA00022838};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Reference proteome {ECO:0000313|Proteomes:UP000271974}.
FT DOMAIN 2..91
FT /note="Ska2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16740"
FT REGION 116..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 39..84
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 117..157
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:RUS70564.1"
SQ SEQUENCE 262 AA; 28657 MW; 522C4331C9B33B83 CRC64;
KFNKADADLK HLTLRLERQL DIGKGNTDQE NPVRLMKEID GVKAEYTNLR QEMAGIQAAQ
KDAVDFLRSQ LLSMSEMVQK LETQTGQRNP ELEETSRVML TELSQLMGVP IEALQAPSGS
AASNTAQSEQ EESEGATASI TASESVTKAT NSVSAEAAEQ PAVEPSAAER RESSSEFVEV
SAEEFASVSE LIRGRSKLED VNRTYSLLWD HFKVQDNTKD LTPKDMNTMG LRVSGATGQA
KLKVLRALKL CKIDKAGNVN LV
//
