ID A0A3S0ZL22_ELYCH Unreviewed; 1326 AA.
AC A0A3S0ZL22;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Dynactin subunit 1 {ECO:0000256|ARBA:ARBA00016574};
GN ORFNames=EGW08_010841 {ECO:0000313|EMBL:RUS81403.1};
OS Elysia chlorotica (Eastern emerald elysia) (Sea slug).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Sacoglossa; Placobranchoidea;
OC Plakobranchidae; Elysia.
OX NCBI_TaxID=188477 {ECO:0000313|EMBL:RUS81403.1, ECO:0000313|Proteomes:UP000271974};
RN [1] {ECO:0000313|EMBL:RUS81403.1, ECO:0000313|Proteomes:UP000271974}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EC2010 {ECO:0000313|EMBL:RUS81403.1};
RC TISSUE=Whole organism of an adult {ECO:0000313|EMBL:RUS81403.1};
RA Cai H., Li Q., Fang X., Li J., Curtis N.E., Altenburger A., Shibata T.,
RA Feng M., Maeda T., Schwartz J.A., Shigenobu S., Lundholm N., Nishiyama T.,
RA Yang H., Hasebe M., Li S., Pierce S.K., Wang J.;
RT "A draft genome assembly of the solar-powered sea slug Elysia chlorotica.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the dynactin 150 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00011010}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RUS81403.1}.
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DR EMBL; RQTK01000339; RUS81403.1; -; Genomic_DNA.
DR STRING; 188477.A0A3S0ZL22; -.
DR Proteomes; UP000271974; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 1.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR InterPro; IPR022157; Dynactin.
DR PANTHER; PTHR18916; DYNACTIN 1-RELATED MICROTUBULE-BINDING; 1.
DR PANTHER; PTHR18916:SF6; DYNACTIN SUBUNIT 1; 1.
DR Pfam; PF01302; CAP_GLY; 1.
DR Pfam; PF12455; Dynactin; 1.
DR SMART; SM01052; CAP_GLY; 1.
DR SUPFAM; SSF74924; Cap-Gly domain; 1.
DR PROSITE; PS00845; CAP_GLY_1; 1.
DR PROSITE; PS50245; CAP_GLY_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Reference proteome {ECO:0000313|Proteomes:UP000271974}.
FT DOMAIN 41..83
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT REGION 90..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1209..1230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 248..529
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 981..1086
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 90..166
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 204..236
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1326 AA; 147610 MW; 8EA3F3B759E9C76D CRC64;
MADADPIGEA AAKMAALAPI KVGTRVEVVG KGVIGTVAYI GNTVFSSGKW IGVVLDEAKG
KNNGTVQGKT YFSCPDEHGI FVRQSQITPL ENQEPPKGSA QASAASTPRP SGLRAPSSRP
TSTPALKKSG LRQPGSMTRS TESIGESSGP GATPSDSKNK QPADPSATPT VRGIKAPRAG
KEAAPKEPSP SNDKPVVATP QPAAPTPKVS SAKSSLENLA PPVQPQTNLG QLGAMSGSQI
SIDERLANVQ QQQEIEGLQV EVKDLNEKLE TLKIKRNEDK AKLKEFEKTK IQLQQLQEYK
SKMQETHTEL QKQLQVSKKE LSEIQHEFEQ YKEEMADVTE TVEMATLDKE MAEEKAETLQ
AEMDTMKEKV EELTLDLELL RGEISDKGTD GVAATFEMKQ LEQQNERMKD ALVKLRDMLN
SEKQDRQRSE KQVEKLEGEL GVLRKDKERL QAQTTELEKE MMDLKEQVDA ALGAEEMVET
LTERNLALED QIKDIVEEKN DLEALNDMNE ELQENARATE LELREELDMK SIKLLELQRK
LDGTQETFSD YDKTLGKFRD LVANLQEQLR SKQEASEIKV DTPTVEIMDF KTKFAETKAY
AKTIDMELRK LDVQLANSHI KMLLSFMPEA FMGRGGDYDA MSVLLMIPRI INKADLLASQ
VKDKFDVTDK IERDDVLKSH KAEQCSFAYN LILLLNTLQS VMAQYESALT SCSTDLFLKV
GTLHPEMSAH EKHLDYYIDL LRKDQLDETI SVDLLEKSIG FFQQLYSVHL SHERVDCTRM
MSNDVRLVLS GCDAITTEVT RLKLLLLPGQ EQSNFSILLK DLETCNNDTR TCARKIKRRL
PQQGSAVATP LKFGKEVQDL LADCCKQVGK ISRLLKVVAA GAMQQAAVMT EQVSKETDRE
GLLPKKFEEL AHEAAGEIYS KENTNAYESL RFSFGTVAGT MNKLANAMEN GEYDFDGTHD
KKDRAPIKLR AEAVKAQASD MEAVRAKVDL KDEEIKELKK MLKMKQEEMS EQQVRIGLVE
KKLENRSREA EDDLKKVQRK LDDSALQLKK KEKEFEETYD ALQSDIDSLE QEKTELKERL
RVLSKNTLLQ NISRQSSVQV PGNGSSTSLN GSMVQESPLL GQQITALKEA LHFNKQELIR
AKAERMKKQM ASLTPLHIPK KPTGMASSTG SVAIGDLPDS VSCKIDLNNL VKKTKNLLGE
ANRLSSSPKV IDISGRKPGM PPATEKAGPM KQLISRTSEI TSLEKFTQEL QVQITMLLAA
NRTGGQVRTD FSTFPTPEFA KMLHEKSSDS MKVGIIQIPT APGKGNVIPV NVRPDQLRQI
HSHLVM
//
