ID A0A3S0ZWL3_ELYCH Unreviewed; 1424 AA.
AC A0A3S0ZWL3;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Nuclear receptor domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=EGW08_007475 {ECO:0000313|EMBL:RUS84791.1};
OS Elysia chlorotica (Eastern emerald elysia) (Sea slug).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Sacoglossa; Placobranchoidea;
OC Plakobranchidae; Elysia.
OX NCBI_TaxID=188477 {ECO:0000313|EMBL:RUS84791.1, ECO:0000313|Proteomes:UP000271974};
RN [1] {ECO:0000313|EMBL:RUS84791.1, ECO:0000313|Proteomes:UP000271974}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EC2010 {ECO:0000313|EMBL:RUS84791.1};
RC TISSUE=Whole organism of an adult {ECO:0000313|EMBL:RUS84791.1};
RA Cai H., Li Q., Fang X., Li J., Curtis N.E., Altenburger A., Shibata T.,
RA Feng M., Maeda T., Schwartz J.A., Shigenobu S., Lundholm N., Nishiyama T.,
RA Yang H., Hasebe M., Li S., Pierce S.K., Wang J.;
RT "A draft genome assembly of the solar-powered sea slug Elysia chlorotica.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RUS84791.1}.
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DR EMBL; RQTK01000193; RUS84791.1; -; Genomic_DNA.
DR STRING; 188477.A0A3S0ZWL3; -.
DR Proteomes; UP000271974; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd06916; NR_DBD_like; 1.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 2.
DR Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR24082; NUCLEAR HORMONE RECEPTOR; 1.
DR PANTHER; PTHR24082:SF283; NUCLEAR HORMONE RECEPTOR HR96; 1.
DR Pfam; PF00105; zf-C4; 2.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 2.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000271974};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 56..131
FT /note="Nuclear receptor"
FT /evidence="ECO:0000259|PROSITE:PS51030"
FT DOMAIN 1129..1377
FT /note="NR LBD"
FT /evidence="ECO:0000259|PROSITE:PS51843"
FT REGION 206..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 624..657
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 722..745
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 810..877
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 922..951
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 963..1003
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1056..1089
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1364..1424
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 206..223
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 624..641
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 642..657
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1364..1416
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1424 AA; 156430 MW; 6304A8885C891E8D CRC64;
MDEEDGRPSF SSQCGGKCDV LKGGRVRCQH CRFQKCISAG MNRKEKPEAV EPAEGQLLCK
VCGDIANGIH FGVITCEGCK KFFRRGLKEN RSYTCKGSMH CSINPRMRNN CRFCRYQKCL
LEGMSREAIK MGRPKKGEVT YSKPSIKKNG LKIPHARNLI STTDKTGVVS SSSMNLMNTA
SSLSSDFEQD EVSSTDAGNG SVLFDHHHPH QHQDTHQHEQ VLHQQHQHQS GGFSSLGSIL
HDCMTVQDWD SGKLELGQAA PSATSADLLV PTATPPSSST GLARSIPDGS ALVGFSMQDE
KQRDRQAFQI HQHFQSQQRQ AIPPQQDSSQ KHVQLLDHFS ESTQSYQSQQ PLEFPENDCC
PDGVPMNRAV KVEDDRLDDG PEGTFSQNVV LETMQNMTVI QNSVDKNAHE KSPPFLSLQQ
QSRHHHDLQN QGPYDIQSLK PIPTYLLPNG NVVSGDALNI VEGGDFDDRD IKYSYTKDMS
VSDTVDAASS LGASVAAKLG GQVLAINMSG RSVTYVPQTQ ETIFLPGVDV GNGEVIGENG
VQILHRPGDI LLSAPQTSFV ATSEGGSIDQ GQNVYSEADL NHAANAPHTS AVHEPYNGLV
KTYLSTPVSS YPPNSFNNLL AVSNHHHQQQ QVLQQQQQQH DVSDSRETDV SADESIGPLL
RHDLDATQDG RNTFRQQPIY QQHFESPREP NISPSQLTPS LLSQPSIIKH ILTNVATSNA
ASSASSGMQE SLSRTTPARK TPISPRSVES LLQQYREAVR LGKPVQLFPD EIAALLSTIT
SEQSRLLRQQ QQQQQKQQLD EVLPPQAQSL TATPTYSPTS VSRPLSQNSS PQSQVQQQQR
RHNVTSPHTS LNRSSPFIAH ASPNFTPNTP SPRPASRNLQ SQHLVVAQRS SPVQDIPLHT
PISAAGYSQG GKTISPILEA RLQQASSPRC KSASSHSDCS SPSDRASVKS NSQEVIMNHN
TYHYKNSNNH SNPSPTGVGL RSPPNSYTLQ QQQQQQLQHH RQQLDLSVAS ATAEVIDDSF
NSSLVRDSAL LHEINRIFLG IDNSCESCAC DRRSAMSGSR DGHGNNWRKK GDGGASTKGG
DGINEPRTSE RMDATLSSLM SPDEFMPELS HNYWHGFKGS SEQKELTAER QQIIQDIMAA
FDNLQRTFVL KDHDQAASPV SRKSNDLLEH WHLIQKRIAR HVVAGQRFCR NIPGYFKIDI
QDRISLGKHV GFGLMVLIAC TEFYDPEFKR FRHIWNWVVQ MQNPLFSYKV HLLQLGERVH
GLGVDSTEAA MLCAISMTSV DTDSTEAAML CAISMTSVDC PDLVKPNIVC HVRDILIGSL
EAYMAAKQAP PDRLAQLLSI MPQVRLMTVW YNNLMKRMSL PSDIATSSAA SRPGGTTTTT
STVSRDGNAS NTSVTSVTRS TTPANSSMSS HSGGRVSAEA TKDK
//
