ID   A0A3S1A109_ELYCH        Unreviewed;       259 AA.
AC   A0A3S1A109;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   22-FEB-2023, entry version 11.
DE   RecName: Full=Defective in cullin neddylation protein {ECO:0000256|RuleBase:RU410713};
GN   ORFNames=EGW08_001129 {ECO:0000313|EMBL:RUS91104.1};
OS   Elysia chlorotica (Eastern emerald elysia) (Sea slug).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Panpulmonata; Sacoglossa; Placobranchoidea;
OC   Plakobranchidae; Elysia.
OX   NCBI_TaxID=188477 {ECO:0000313|EMBL:RUS91104.1, ECO:0000313|Proteomes:UP000271974};
RN   [1] {ECO:0000313|EMBL:RUS91104.1, ECO:0000313|Proteomes:UP000271974}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EC2010 {ECO:0000313|EMBL:RUS91104.1};
RC   TISSUE=Whole organism of an adult {ECO:0000313|EMBL:RUS91104.1};
RA   Cai H., Li Q., Fang X., Li J., Curtis N.E., Altenburger A., Shibata T.,
RA   Feng M., Maeda T., Schwartz J.A., Shigenobu S., Lundholm N., Nishiyama T.,
RA   Yang H., Hasebe M., Li S., Pierce S.K., Wang J.;
RT   "A draft genome assembly of the solar-powered sea slug Elysia chlorotica.";
RL   Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Neddylation of cullins play an essential role in the
CC       regulation of SCF-type complexes activity.
CC       {ECO:0000256|RuleBase:RU410713}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RUS91104.1}.
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DR   EMBL; RQTK01000018; RUS91104.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3S1A109; -.
DR   STRING; 188477.A0A3S1A109; -.
DR   Proteomes; UP000271974; Unassembled WGS sequence.
DR   Gene3D; 1.10.238.200; Cullin, PONY binding domain; 1.
DR   Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR   Gene3D; 1.10.238.10; EF-hand; 1.
DR   InterPro; IPR014764; DCN-prot.
DR   InterPro; IPR042460; DCN1-like_PONY.
DR   InterPro; IPR005176; PONY_dom.
DR   InterPro; IPR009060; UBA-like_sf.
DR   PANTHER; PTHR12281:SF32; DCN1-LIKE PROTEIN; 1.
DR   PANTHER; PTHR12281; RP42 RELATED; 1.
DR   Pfam; PF03556; Cullin_binding; 1.
DR   Pfam; PF14555; UBA_4; 1.
DR   SUPFAM; SSF46934; UBA-like; 1.
DR   PROSITE; PS51229; DCUN1; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000271974};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT   DOMAIN          60..248
FT                   /note="DCUN1"
FT                   /evidence="ECO:0000259|PROSITE:PS51229"
SQ   SEQUENCE   259 AA;  30495 MW;  34B93F46B0FACC86 CRC64;
     MQRLKSSQKD KVRQFVAFTQ TGEKTAINCL CAHEWKLDVA VDNYFIAPDR YNTAESRSSV
     DKRKIEALWQ RYKDPGDEDK MLVDGVMQFL EDLQLNPESR TVLILAWRFK AKTQCEFTKE
     EFVQGMLEMG CDSVDKLRAK CNMLEHEIRD PNSFKDFYQF TFNYAKNPEQ KGLDQEMAIA
     YWNIVLTGRF KFLDLWCKFL QENHKRSIPK DTWNLLLDFC NMINDDMSNY DEEGAWPVLI
     DDFVEYARPV VHGSRSTVV
//