ID A0A3S1AFL6_ELYCH Unreviewed; 411 AA.
AC A0A3S1AFL6;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 13-SEP-2023, entry version 17.
DE RecName: Full=LIM zinc-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=EGW08_001679 {ECO:0000313|EMBL:RUS90591.1};
OS Elysia chlorotica (Eastern emerald elysia) (Sea slug).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Sacoglossa; Placobranchoidea;
OC Plakobranchidae; Elysia.
OX NCBI_TaxID=188477 {ECO:0000313|EMBL:RUS90591.1, ECO:0000313|Proteomes:UP000271974};
RN [1] {ECO:0000313|EMBL:RUS90591.1, ECO:0000313|Proteomes:UP000271974}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EC2010 {ECO:0000313|EMBL:RUS90591.1};
RC TISSUE=Whole organism of an adult {ECO:0000313|EMBL:RUS90591.1};
RA Cai H., Li Q., Fang X., Li J., Curtis N.E., Altenburger A., Shibata T.,
RA Feng M., Maeda T., Schwartz J.A., Shigenobu S., Lundholm N., Nishiyama T.,
RA Yang H., Hasebe M., Li S., Pierce S.K., Wang J.;
RT "A draft genome assembly of the solar-powered sea slug Elysia chlorotica.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RUS90591.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; RQTK01000029; RUS90591.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3S1AFL6; -.
DR STRING; 188477.A0A3S1AFL6; -.
DR Proteomes; UP000271974; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd09401; LIM_TLP_like; 1.
DR CDD; cd21886; SARAH_RASSF2-like; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 1.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR033614; RASSF1-6.
DR InterPro; IPR011524; SARAH_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR22738:SF15; LD40758P; 1.
DR PANTHER; PTHR22738; RASSF; 1.
DR Pfam; PF00412; LIM; 1.
DR Pfam; PF16517; Nore1-SARAH; 1.
DR Pfam; PF00788; RA; 1.
DR SMART; SM00132; LIM; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 1.
DR PROSITE; PS50200; RA; 1.
PE 4: Predicted;
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000271974};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 3..74
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 205..292
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT REGION 140..170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..170
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 411 AA; 46300 MW; 606C3FCC77923AC1 CRC64;
MNKNCAGCGK PVYFAERKTS LGREWHPSCL KCRECGKVLS PGQHAEYVNP LYLVLLTYIN
VLFCFLCRQE MLDKLAEFNK YYEGKVHHHM RAQQADDGSV FVEGPLRVYW GLSRPIQLAH
CDNIPPAPIS QWRHSLHVSA DSPSLRRTGS PSRKSRDLDD LLSPSSSDDV VRRKKGGVRK
FKTVAYRGGD QPSKWKRASI NGHIFNFDTS VFTPVLGSCT SVTVDGTLNS LEVIETLLDK
FKVQNSADEY VLSIVNEEGE RLLTNRDRPL LERLKLGPDE TVGKIFIKER EIIQEKGVGE
LVVSANVKAS LLTGDKDSID GGADGSPGYG RSIRSSSIKI PIRETEEEEN LPHDVEQLLI
LPEPVLRGLL VKYHNDEELE VKKIRARYDV FRQRMTKRIY ELLSNSTSST A
//
