ID   A0A3S1AYK2_ELYCH        Unreviewed;       225 AA.
AC   A0A3S1AYK2;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   13-SEP-2023, entry version 13.
DE   RecName: Full=Growth factor receptor-bound protein 2 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=EGW08_016757 {ECO:0000313|EMBL:RUS75489.1};
OS   Elysia chlorotica (Eastern emerald elysia) (Sea slug).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Panpulmonata; Sacoglossa; Placobranchoidea;
OC   Plakobranchidae; Elysia.
OX   NCBI_TaxID=188477 {ECO:0000313|EMBL:RUS75489.1, ECO:0000313|Proteomes:UP000271974};
RN   [1] {ECO:0000313|EMBL:RUS75489.1, ECO:0000313|Proteomes:UP000271974}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EC2010 {ECO:0000313|EMBL:RUS75489.1};
RC   TISSUE=Whole organism of an adult {ECO:0000313|EMBL:RUS75489.1};
RA   Cai H., Li Q., Fang X., Li J., Curtis N.E., Altenburger A., Shibata T.,
RA   Feng M., Maeda T., Schwartz J.A., Shigenobu S., Lundholm N., Nishiyama T.,
RA   Yang H., Hasebe M., Li S., Pierce S.K., Wang J.;
RT   "A draft genome assembly of the solar-powered sea slug Elysia chlorotica.";
RL   Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RUS75489.1}.
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DR   EMBL; RQTK01000738; RUS75489.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3S1AYK2; -.
DR   STRING; 188477.A0A3S1AYK2; -.
DR   Proteomes; UP000271974; Unassembled WGS sequence.
DR   CDD; cd09941; SH2_Grb2_like; 1.
DR   CDD; cd11804; SH3_GRB2_like_N; 1.
DR   Gene3D; 3.30.505.10; SH2 domain; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 2.
DR   InterPro; IPR043539; Grb2-like.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR46037:SF1; GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2; 1.
DR   PANTHER; PTHR46037; PROTEIN ENHANCER OF SEVENLESS 2B; 1.
DR   Pfam; PF00017; SH2; 1.
DR   Pfam; PF00018; SH3_1; 2.
DR   PRINTS; PR00499; P67PHOX.
DR   PRINTS; PR00401; SH2DOMAIN.
DR   PRINTS; PR00452; SH3DOMAIN.
DR   SMART; SM00252; SH2; 1.
DR   SMART; SM00326; SH3; 2.
DR   SUPFAM; SSF55550; SH2 domain; 1.
DR   SUPFAM; SSF50044; SH3-domain; 2.
DR   PROSITE; PS50001; SH2; 1.
DR   PROSITE; PS50002; SH3; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000271974};
KW   SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          1..58
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          60..153
FT                   /note="SH2"
FT                   /evidence="ECO:0000259|PROSITE:PS50001"
FT   DOMAIN          160..219
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
SQ   SEQUENCE   225 AA;  25824 MW;  51E2E9329268799C CRC64;
     MEAVALHPFT ATADDELSFK KGSVLKILST FDDKNWYRAE LNGKEGYVPH NYIQMCPHAW
     YVGKISRSKA EEMLLRTEQP DGAFLVRNSE SAPGEFSITV KFQDGVQHFK VLRDGIGKYF
     LWVIKFNSIN ELVNHHRDVT VSRSHDIYFK DMVNHDLGPV GVQYVRATYD FNAEGIDELG
     FHTGEVIKVT NKVDEAWWRG QLNGQEGMFP ASYVERLPDD YQQNL
//