ID A0A3S1BMS5_ELYCH Unreviewed; 456 AA.
AC A0A3S1BMS5;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=GPR180/TMEM145 transmembrane domain-containing protein {ECO:0000259|Pfam:PF10192};
GN ORFNames=EGW08_007811 {ECO:0000313|EMBL:RUS84427.1};
OS Elysia chlorotica (Eastern emerald elysia) (Sea slug).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Sacoglossa; Placobranchoidea;
OC Plakobranchidae; Elysia.
OX NCBI_TaxID=188477 {ECO:0000313|EMBL:RUS84427.1, ECO:0000313|Proteomes:UP000271974};
RN [1] {ECO:0000313|EMBL:RUS84427.1, ECO:0000313|Proteomes:UP000271974}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EC2010 {ECO:0000313|EMBL:RUS84427.1};
RC TISSUE=Whole organism of an adult {ECO:0000313|EMBL:RUS84427.1};
RA Cai H., Li Q., Fang X., Li J., Curtis N.E., Altenburger A., Shibata T.,
RA Feng M., Maeda T., Schwartz J.A., Shigenobu S., Lundholm N., Nishiyama T.,
RA Yang H., Hasebe M., Li S., Pierce S.K., Wang J.;
RT "A draft genome assembly of the solar-powered sea slug Elysia chlorotica.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RUS84427.1}.
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DR EMBL; RQTK01000206; RUS84427.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3S1BMS5; -.
DR Proteomes; UP000271974; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR GO; GO:0019236; P:response to pheromone; IEA:InterPro.
DR InterPro; IPR047831; GPR180/TMEM145.
DR InterPro; IPR019336; GPR180/TMEM145_TM.
DR PANTHER; PTHR23252:SF29; INTEGRAL MEMBRANE PROTEIN GPR180; 1.
DR PANTHER; PTHR23252; INTIMAL THICKNESS RECEPTOR-RELATED; 1.
DR Pfam; PF10192; GpcrRhopsn4; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000271974};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 189..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 221..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 304..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..356
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 404..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 160..421
FT /note="GPR180/TMEM145 transmembrane"
FT /evidence="ECO:0000259|Pfam:PF10192"
SQ SEQUENCE 456 AA; 51410 MW; 0BE3100983FA8FC1 CRC64;
MCNQLLPHDL NNSRSSFAPR TFVIGFQLRL SFIILLISSF CEAKTVHGVF NTYSAQAEKG
QYVTSFAFHG DAVLNFTVNA TGVESKLYLF VSEDWKDAAG DSNCYRRLGK ARAIIRIDSL
SRSQPVAHYM YPRIWHVVYA DLYTCEAGRP TLPEERPNLI QYRIELLNPD CLGNPTEHFG
DQDTGLLKFY QALTLTYFVV ACVVAPRLWD SLSKGGPMQL VMQLLTCSMG LQFAAACSVI
VHFYRYSKDG IGSPGIELLS ELLDMLSQLT MLLMLLSLSL GWTLASAHSV CRYSHLRSIS
QKPAARLVFV LGILQGLLFM WEQSQDQSLR LYRAQRSYAG LSLAALRILL AAMFAVKLRA
LVAAERSKLK RQFYNSFTKL CMLWFLCYPV VVVCSMLFAE YLRFKLITMG VVLCQSAAGV
LLYRLFLSRS LYWEVSALSS SLPIRLDQRF GISAYS
//
