ID A0A3S1JAX4_9BACT Unreviewed; 622 AA.
AC A0A3S1JAX4;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Mechanosensitive ion channel {ECO:0000313|EMBL:NSL89424.1};
GN ORFNames=ECE50_021460 {ECO:0000313|EMBL:NSL89424.1};
OS Chitinophaga solisilvae.
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Chitinophaga.
OX NCBI_TaxID=1233460 {ECO:0000313|EMBL:NSL89424.1, ECO:0000313|Proteomes:UP000281028};
RN [1] {ECO:0000313|EMBL:NSL89424.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Mgbs1 {ECO:0000313|EMBL:NSL89424.1};
RA Goh C.B.S., Lee M.S., Parimannan S., Pasbakhsh P., Yule C.M., Rajandas H.,
RA Loke S., Croft L., Tan J.B.L.;
RT "Chitinophaga laudate sp. nov., isolated from a tropical peat swamp.";
RL Submitted (MAY-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NSL89424.1}.
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DR EMBL; RIAR02000001; NSL89424.1; -; Genomic_DNA.
DR Proteomes; UP000281028; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0008381; F:mechanosensitive monoatomic ion channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR045275; MscS_archaea/bacteria_type.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR PANTHER; PTHR30221:SF18; SLL0590 PROTEIN; 1.
DR PANTHER; PTHR30221; SMALL-CONDUCTANCE MECHANOSENSITIVE CHANNEL; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000281028};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 426..491
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 503..584
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
SQ SEQUENCE 622 AA; 70272 MW; 509DC31221B05B34 CRC64;
MKLSIVLFLT AVLTTTVIRT FAQTDSSKAQ QDSITNTHLE QTTQLLRQND SLVKADAAER
NTLLQQIESL KNDNDKRKQE LQQQLRNIDQ TDSLRKVKQL ERIKQLKAIT NGIPVAPFQD
TLFRIYNRLG AQQPSDRAAN IERKLQQLEH DPFFAADSLK PAANENNVDI IYNDIILMTV
TDDDALWLER DKSSVAAEYA AIMRKEILLQ KDQNSLKNVL IRIGWLALIL AVFGLIVYGI
NRVFKRIRIR LIKRKEEYFK GVKVKGYALL NQQKQLGLFY SALKIIRIVL ILFIFYITLP
LIFSIFPWTK GIADKLIDWT LSPIKAILAG VLQYLPKLLT ILVIYIVTRY LVRLVNYLAA
EIACGNLQIK GFYADWAMPT ASGIKFLLYA FMFVVIFPYL PGSDSKIFQG VSVFLGILFS
LGSSSAISNV VAGFVITYMR PFKIGDRIKI GDITGDVIEK TLLVTRLRTI KNEEITVPNA
SVLNGHTINF TSSSKDLGLI LHTTVTIGYD VPWKQVQELL IRAALATDGI LKDRPPFVLQ
TALNDFSVAY EINAFTDQSH KMAVIYSGLH QQIQDQFNAA GIEIMSPQYH AHRDGSASTI
PADYLPKDYA PQPFRVDINK QP
//
