ID   A0A3S2LYI3_ORYJA        Unreviewed;       210 AA.
AC   A0A3S2LYI3;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=Claudin {ECO:0008006|Google:ProtNLM};
GN   ORFNames=OJAV_G00141880 {ECO:0000313|EMBL:RVE64023.1};
OS   Oryzias javanicus (Javanese ricefish) (Aplocheilus javanicus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=123683 {ECO:0000313|EMBL:RVE64023.1, ECO:0000313|Proteomes:UP000283210};
RN   [1] {ECO:0000313|EMBL:RVE64023.1, ECO:0000313|Proteomes:UP000283210}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RS831 {ECO:0000313|EMBL:RVE64023.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:RVE64023.1};
RA   Lopez-Roques C., Donnadieu C., Bouchez O., Klopp C., Cabau C., Zahm M.;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:RVE64023.1, ECO:0000313|Proteomes:UP000283210}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RS831 {ECO:0000313|EMBL:RVE64023.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:RVE64023.1};
RA   Herpin A., Takehana Y., Naruse K., Ansai S., Kawaguchi M.;
RT   "A chromosome length genome reference of the Java medaka (oryzias
RT   javanicus).";
RL   Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell junction, tight junction
CC       {ECO:0000256|ARBA:ARBA00004435}.
CC   -!- SIMILARITY: Belongs to the claudin family.
CC       {ECO:0000256|ARBA:ARBA00008295}.
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DR   EMBL; CM012450; RVE64023.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3S2LYI3; -.
DR   Proteomes; UP000283210; Chromosome 14.
DR   GO; GO:0005923; C:bicellular tight junction; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   Gene3D; 1.20.140.150; -; 1.
DR   InterPro; IPR006187; Claudin.
DR   InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
DR   PANTHER; PTHR12002; CLAUDIN; 1.
DR   PANTHER; PTHR12002:SF192; CLAUDIN-RELATED; 1.
DR   Pfam; PF00822; PMP22_Claudin; 1.
DR   PRINTS; PR01077; CLAUDIN.
PE   3: Inferred from homology;
KW   Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000283210};
KW   Tight junction {ECO:0000256|ARBA:ARBA00022427};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        79..100
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        121..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        164..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   210 AA;  22491 MW;  0D35AFFEE11F4663 CRC64;
     MVSTKKQLLG LALAIFGVLG AIVICAVPCW KVTAFIGANI VTSQVIWEGI WINCVTQSTG
     QMQCKFYDSL LALPQDLQAA RALVIIAIVA GVLGIVLAVF GGKCTNFITD ENQKVKVAIA
     AGIVFLIAGL LVMVPVCWTA STIVQDFYNP MLVEAQKREL GASLYIGWAS AALLFLGGGL
     LCSSCPPREE YYAQDIKYSK TQSASSKEYV
//