ID A0A3S2U7Q2_9BURK Unreviewed; 630 AA.
AC A0A3S2U7Q2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Propionate--CoA ligase {ECO:0000313|EMBL:RVT50398.1};
DE EC=6.2.1.17 {ECO:0000313|EMBL:RVT50398.1};
GN ORFNames=ENE75_15400 {ECO:0000313|EMBL:RVT50398.1};
OS Rubrivivax albus.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Rubrivivax.
OX NCBI_TaxID=2499835 {ECO:0000313|EMBL:RVT50398.1, ECO:0000313|Proteomes:UP000288178};
RN [1] {ECO:0000313|EMBL:RVT50398.1, ECO:0000313|Proteomes:UP000288178}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ICH-3 {ECO:0000313|EMBL:RVT50398.1,
RC ECO:0000313|Proteomes:UP000288178};
RA Chen W.-M.;
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RVT50398.1}.
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DR EMBL; SACT01000005; RVT50398.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3S2U7Q2; -.
DR OrthoDB; 9766486at2; -.
DR Proteomes; UP000288178; Unassembled WGS sequence.
DR GO; GO:0050218; F:propionate-CoA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0019629; P:propionate catabolic process, 2-methylcitrate cycle; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR012694; Propion_PrpE.
DR NCBIfam; TIGR02316; propion_prpE; 1.
DR PANTHER; PTHR43347; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43347:SF3; ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:RVT50398.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000288178}.
FT DOMAIN 3..57
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 59..446
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 511..594
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 630 AA; 68890 MW; 55AA327C30848F98 CRC64;
MSYADFYRRS IEDRDAFWAE QAALIDWQTP FTQVCDHSQP PFARWFVGGT TNLCHNAVDR
HAATHPERNA LIFVSTETNQ ERIYSFAELQ AEVERMAAML QGLGVKQGDR VLVYMPMIPE
AAFAMLACTR IGALHSVVFG GFASHSLASR IDDAEPAVIV SADAGSRGGK VVPYKGLLDE
AIRLATHKPA KVLMVNRGLA EMPMTVGRDE DYAALREQHL DARVPCTWVA ADHPSYTLYT
SGTTGKPKGV QRDTGGYAVA LAASMKHIFL GNPGETYFST SDIGWVVGHS YIVYGPLIAG
MATIMYEGLP TRPDAAVWWS LVEKYKVTSM FSAPTAVRVL KKQDPAALKQ HDLSSLRALF
LAGEPLDEPT AQWIAEALGR PIIDNYWQTE TGWPILTICN GVERAPSKFG SPGKAVYGYD
VKLFDENTGE ELTGAHQKGV LAIEGPLPPG CLQTVWRDDD RFVKTYWSSI PGRQVYSTFD
WAIRDDDGYY FILGRTDDVI NVAGHRLGTR EIEESIASHP NVAEVAVVGV ADNLKGQVAM
AFAVLKDTTA LTDANAALKL EGEIMKVVDG QLGAVARPAR VRFVTVLPKT RSGKLLRRAI
QAVCESRDPG DLTTIEDPTA LQQIKDLVGG
//
