ID A0A3S2V614_9SPHN Unreviewed; 1036 AA.
AC A0A3S2V614;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Efflux RND transporter permease subunit {ECO:0000313|EMBL:RVU04486.1};
GN ORFNames=EOE18_11885 {ECO:0000313|EMBL:RVU04486.1};
OS Novosphingobium umbonatum.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Novosphingobium.
OX NCBI_TaxID=1908524 {ECO:0000313|EMBL:RVU04486.1, ECO:0000313|Proteomes:UP000282837};
RN [1] {ECO:0000313|EMBL:RVU04486.1, ECO:0000313|Proteomes:UP000282837}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FSY-9 {ECO:0000313|EMBL:RVU04486.1,
RC ECO:0000313|Proteomes:UP000282837};
RA Chen W.-M.;
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. {ECO:0000256|ARBA:ARBA00010942}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RVU04486.1}.
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DR EMBL; SACO01000008; RVU04486.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3S2V614; -.
DR OrthoDB; 9758757at2; -.
DR Proteomes; UP000282837; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR InterPro; IPR004763; CusA-like.
DR NCBIfam; TIGR00914; 2A0601; 1.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF24; CATION EFFLUX SYSTEM (ACRB_ACRD_ACRF FAMILY); 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000282837};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 348..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 438..462
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 474..496
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 541..563
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 870..891
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 898..919
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 931..951
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 972..991
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1003..1022
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 609..634
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1036 AA; 111638 MW; 814CD90EF5DC3E5F CRC64;
MITGLIRAAL KQRLIVVVVA LALLGFGFAA VQQLSVDAFP DVTNVQVQIA TEASGRSPEE
VERMATAPIE VAMTGLPGLE EMRSLNKPGL SLITLVFTEQ TNVYFARQLV MERLAELGPK
LTPGIAPVLG PVSTGLGEVY QYTLDRPDDK GRQLTPEELT QRRLVQDWVV RPLLRSISGV
AEINSQGGFP RQYQVLVNPD RLRHYQVSVA DVFSAVARNN ANAGGGVLPQ FAEQYLIRGV
GLVKNEEDLR NIVIRENASQ PLYLRDVAEV KIGAGVREGA IIQNGTSEAV GGVVMMMAGG
NAKQIVSRVK EKVEQINSKG MLPDGLKIVP YYDRSELVDA ALHTVTKVLM EGIVLVVVIL
FLFLGDIRSS LIVVATLVLT PLITFMAMNK LGISANLMSL GGLAIAIGLM VDGSVVVVEN
AFAQLGTSAA KGQTKARVIL QAVVEVATPV IFGVGVIILV FLPLMTLQGM EGKMFAPLAY
TIAIALAVSL VLSLTLTPVL STYLLKAPEH DGDHDTKIIA WMKARYLKML GWALGNERKT
VAYTLGALLF AVALFPFLGT AFIPEMKEGS LVPGINRVPN IALDESIRIE MEAMRLVMQV
PGVKSAVSGV GRGESAADPQ GPNESTPIVS LKPRDEWPDG WDQDDIAEAM REKLKALPGI
QIVMAQPISD RVDEMVTGVR SDIAVKVFGD DLEQLKAKAE EIARVARSLK GAEDLRIEKI
SGQQYLSIDI DRQAVARYGL NVADVNDLIE TAVGGKAATE IFEGERRFPA VVRLPADRRA
NIQAISDLLV PSPGGAQVRL ADVAHISVMD GPAQISRESG KRRIVIGMNV KGRDLGGFVA
ELQQKVGAQV KLPEGYYLEW GGQFQNMERA LGHLMIIVPI TVAAIFFLLF VLFNSIRLAS
LIITVLPFAS IGGVIGLFVS GEYLSVPASV GFIALWGIAV LNGVVLVSYI RKLREEGMSV
AEAVRHGATM RFRPVMMTAT VALLGLIPFL FSTGPGAEVQ RPLAIVVIGG IITSTLLTLL
VLPTIYRFFD SEPLEA
//
